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2014 Important Dates

Workshop Proposals Deadline November 13

2015 Important Dates

Abstract Submission Opens February 13
Conference Registration Opens February 18
Abstract Submission Deadline April 16
Financial Aid Deadline April 16
Abstract Revision Deadline April 17
Platform/Poster Assignments Online May 20
Early Meeting Registration May 21
Housing Reservation May 21
Abstract Search and Program Planner Online June 14

Poster Session Listing



Physiology - Aging and Stress

194A. Genetic and Biochemical Approaches to Determine the Role of APL-1, an Ortholog of human APP. Adanna G. Alexander, Chris Li.

195B. Guarana (Paullinia cupana Mart) extends lifespan and modulates some gene expression levels in Caenorhabditis elegans. Leticia Arantes, Marina Machado, Daniele Zamberlan, Felix Soares, Michael Aschner.

196C. Investigating the role of progeric gene inactivations in synaptic maintenance of DA9 neurons in C.elegans. Maria Armakola, Gary Ruvkun.

197A. Involvement of daf-16, skn-1 and trxr-1 genes in the stress resistance produced by 4-phenylseleno-7-chloroquinoline exposure in Caenorhabditis elegans. Daiana Avila, Willian Salgueiro, Diego Alves, Maurício Xavier.

198B. Modulation of stress resistance and longevity by the transthyretin-like gene ttr-1. Dena Block, Dustin Cox, Kwame Twumasi-Boateng, Michael Shapira.

199C. What are they Choosing? Linking Food Preference to Life-History Outcomes. Ben Blue, Stephen Banse, Patrick Phillips.

200A. Nuclear DNA damage signaling by ATL-1 and CSB-1 modulates longevity in the C. elegans Mit mutants. Milena Girotti, Shylesh Bhaskaran, Jeffery Butler, Sandra Becerra, Megan Borror, Shane Rea.

201B. Roles of sphingolipid signaling in life history traits, aging, and healthsapn in C. elegans. Jaylene Brown, Abby Nolan, Dustin Servello, Brandon Hark, Trisha Staab, Jason Chan.

202C. Specific RNA interference in Caenorhabditis elegans by ingested dsRNA expressed in Bacillus subtilis. Yelena Budovskaya, Marco Lezzerini, Koen van de Ven, Martijn Veerman, Stanley Brul.

203A. Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. Kristopher Burkewitz, Ianessa Morantte, Heather Weir, Robin Yeo, Yue Zhang, Frank Huynh, Olga Ilkayeva, Matthew Hirschey, Ana Grant, William Mair.

204B. The progranulin cleavage products, granulins, exacerbate toxicity in a C. elegans model of TDP-43 neurodegeneration. Dominique Salazar, Victoria Butler, Andrea Argouarch, Tsung-Yuan Hsu, Nakamura Ayumi, Seeley William, Bruce Miller, Aimee Kao.

205C. Progranulin and its cleavage products, the granulins, are reciprocal regulators of lysosome function and organismal stress response. Victoria Butler, Meredith Judy, Tsung-Yuan Hsu, Dominique Salazar, Aimee Kao.

206A. Regulation of Stress Physiology and Longevity by the eIF3 Translation Initiation Complex in C. elegans. Douglas Cattie, Claire E. Richardson, Kirthi C. Reddy, Dennis H. Kim.

207B. Spatial and temporal analysis of autophagy in organismal aging. Jessica T. Chang, Joseph H. Davis, Malene Hansen.

208C. Mitochondrial sirtuins and oxidative stress response in C. elegans. Sarah Chang, Wendy Hanna-Rose.

209A. RIL-1 influences life span through suppression of mitochondrial electron transport chain in C. elegans. Chieh Chen, Ao-Lin Hsu.

210B. Transcriptional and Post-transcriptional Analyses of the Synergistically Extended Lifespan by Mutations in daf-2 and rsks-1 in C. elegans. Jianfeng Lan, Jarod Rollins, Di Wu, Xuan Zhang, Fen Chen, Pankaj Kapahi, Aric Rogers, Di Chen.

211C. Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress. Yee Lian Chew, Jürgen Götz, Hannah Nicholas.

212A. Activation of the innate immune response protects against neurodegeneration in C. elegans. Madhusudana Chikka, Kyle Dombeck, Veena Prahlad.

213B. The ASI paradox. Peter Chisnell, Cynthia Kenyon.

214C. Worm life balance – H3K27 methylation and lifespan extension. Karolina Chocian, Julien Vandamme, Lisa Salcini, Jane Mellor, Alison Woollard.

215A. Analysis of quiescence during aging in insulin/insulin-like signaling mutants using a microfabricated WorMotel multi-well device. Matthew Churgin, Christopher Fang-Yen.

216B. The germ cell DNA damage response actively curtails C. elegans lifespan. Evan Lister-Shimauchi, Veronica Gomez-Godinez, Michael Berns, Olivier Cinquin.

217C. The effect of FUdR on fatty acid composition and aging in C. elegans. Raven Conyers, Xun Shi, Jennifer. Watts.

218A. Screening for interactions among multiple stressors using response to light as a survival metric. Tim Crombie, David Julian.

219B. Spatial and temporal microfluidics study of the neuronal regulation and modes of activation of the heat shock stress response. Erin Dahlstrom, Erel Levine.

220C. Identification of Pathways Responsible for Reduced Protein Synthesis-induced Lifespan. Hans Dalton, Chia-An Yen, Sean Curran.

221A. The homeodomain protein kinase, HPK-1 influences aging and is a central component of the heat shock response . Ritika Das, Richard Kim, Elliot Schwartz, Andrew Samuelson.

222B. Identification of microRNA-239 target genes and their role in promoting longevity in C. elegans. Manasa Basavaraju, Alexandre de Lencastre.

223C. MicroRNA Functions in C. elegans Models of Neurodegenerative Diseases. Kaushik Muralidharan, Alexandre de Lencastre.

224A. Biofilm proficiency enhances gut colonization and lifespan in Caenorhabditis elegans. Verónica Donato, Roberto Grau.

225B. A role for neuropeptide signaling in regulating C. elegans response to anoxia. Shachee Doshi, John J. Flibotte, Robert G. Kalb.

226C. O-GlcNAc cycling plays a crucial role in germline plasticity and acts in coordination with fatty acid β-oxidation to regulate ARD entry in C. elegans. Moriah Eustice, John Hanover.

227A. Regulation of protein homeostasis by microRNAs in Caenorhabditis elegans. Fabian Finger, Thorsten Hoppe.

228B. The DAF-7/TGF-β pathway is required for lifespan extension mediated by dietary restriction in C. elegans. Marissa Fletcher, Dennis Kim.

229C. Modulation of aging characteristics with an anti-aging compound. Nicola Fox, EJC Mellor.

230A. Molecular Jekyll and Hyde: The Opposing Roles of TCER-1/TCERG1 in Regulating Lifespan and Stress Resilience. Francis RG Amrit, Laura Steenberge, Brooke McClendon, Judith Yanowitz, Arjumand Ghazi.

231B. Glucose Induces Sensitivity to Oxygen Deprivation & is Modulated via Insulin Signaling and Lipid Biosynthesis in C.elegans. Anastacia M. Garcia, Mary L. Ladage, Rajeev K. Azad, Pamela A. Padilla.

232C. Identification of trinucleotide-repeat RNA toxicity pathways in C. elegans. S. Garcia, Y. Tabach, G. Lourenço, M. Armakola, G. Ruvkun.

233A. Autophagy in the Intestine Acts to Influence Healthspan and Longevity During Dietary Restriction. Sara Gelino, Jessica Chang, Malene Hansen.

234B. Transcription Factors that Coordinate Lipid Synthesis and Breakdown to Ensure Metabolic Homeostasis and Longevity. Francis RG Amrit, Elizabeth Steenkiste, Ramesh Ratnappan, Shaw-Wen Chen, T. Brooke McClendon, Carissa P. Olsen, Judith L. Yanowitz.

235C. Measuring Caenorhabditis elegans food intake and the absorption of dietary amino acids in 96-well microtiter plates. Rafael Gomez-Amaro, Elizabeth Valentine, Maria Carretero, Sarah LeBoeuf, Sunitha Rangaraju, Caroline Broaddus, Gregory Solis, James Williamson, Michael Petrascheck.

236A. Chemically induced oxidative stress affects ASH neuronal function and C. elegans behavior. Eleni Gourgou, Nikos Chronis.

237B. Genetic dissection of mechanisms that contribute to extrusion of neurotoxic aggregates from neurons. Ryan Guasp, Ilija Melentijevic, Meghan Arnold, Girish Harinath, Monica Driscoll.

238C. Sensory Neuronal Signaling Protects from Proteotoxic Stress to Promote Longevity. Gabriel Guerrero, Martin Denzel.

239A. Caenorhabditis Intervention Testing Program: Gateway to the Fountain of Youth. Patrick Phillips, Monica Driscoll, Gordon Lithgow, Max Guo, Jailynn Harke.

240B. A C. elegans model to elucidate the role of mitochondrial DNA mutation in disease. Suraiya Haroon, Tali Gidalevitz, Marc Vermulst.

241C. Quantitative Behavioral Measurements of Individual Aging Worms Reveal Lifespan-Altering Insulin Pathway Mutants Do Not Affect Healthspan. Stephen Helms, Esther Lohrmann, Jana Koers, Marco Lezzerini, Greg Stephens, Tom Shimizu, Yelena Budovskaya.

242A. Insulin-like signaling and other aging regulators mediate effects of dietary restriction on progeny size and environmental anticipation. Jon Hibshman, Anthony Hung, L. Ryan Baugh.

243B. A protective role of sensory perception through amine neurotransmitters in C. elegans. H. Hoshikawa, M. Uno, H. Yoshimura, S. Honjoh, E. Nishida.

244C. Neural Activity and CaMKII Protect Neuronal Mitochondria from Age-Dependent Fragmentation in C. elegans. Hao-Ching Jiang, Jiun-Min Hsu, Chien-Ping Yen, Chi-Chao Chao, Ruey-Hwa Chen, Chun-Liang Pan.

245A. New longevity genes revealed by integrative analysis of isoform-specific DAF-16/FoxO mutants. Albert Chen, Chunfang Guo, Omar Itani, Breane Budaitis, Travis Williams, Christopher Hopkins, Richard McEachin, Manjusha Pande, Ana Grant, Sawako Yoshina, Shohei Mitani, Patrick Hu.

246B. New longevity genes revealed by integrative analysis of daf-2 and glp-1 mutants. Albert Chen, Joseph Kruempel, Ian Waters, Chunfang Guo, Manjusha Pande, Ana Grant, Richard McEachin, Patrick Hu.

247C. BRAP-2 regulates SKN-1/ELT-3 in response to oxidative stress through the ERK/MAPK pathway. Queenie Hu, Lesley T. MacNeil, Dayana R. D’Amora, Marian Walhout, Terrance J. Kubiseski.

248A. The RNA binding protein TIAR-1 is important to protect germ cells from stress. Gabriela Huelgas-Morales, Carlos G. Silva-García, Laura S. Salinas-Velázquez, David Greenstein, Rosa E. Navarro.

249B. The role of cholesterol in DAF-16 nuclear localization and fasting-induced longevity in C. elegans. Akiko Ihara, Masaharu Uno, Koichi Miyatake, Sakiko Honjoh, Eisuke Nishida.

250C. Investigation of TORC1-inhibition dependent SKN-1/Nrf activity and its effect on longevity . Meltem Isik, Keith T. Blackwell.

251A. GLP-1/Notch longevity is not equivalent to germline laser ablation mediated longevity. Philipp S. Jaeger, Oezlem Karalay, Shuhei Nakamura, Kayo Nakamura, Christian Latza, Adam Antebi.

252B. Hyperoxia effects on development and reproduction. Gholamali Jafari, Jason Pitt, Zhongyu Li, Daniela Ayon, Matt Kaeberlein.

253C. Extended starvation during L1 arrest appears to reduce fitness in the exposed animals but cause potentially adaptive effects in their descendants. James M. Jordan, Meghan A. Jobson, Jon D. Hibshman, Moses A. Sandrof, L. Ryan Baugh.

254A. A decrease in movement at a defined moment in life predicts death. Katharina Jovic, Rosanne Bartels, Rita J. M. Volkers, Mark G. Sterken, L. Basten Snoek, Jan E. Kammenga.

255B. 20-hydroxyecdysone modulates energy metabolism and extends healthspan in C. elegans. Shaunak Kamat, Brittany Graf, Slavko Komarnytsky, James Aramini, Monica Driscoll.

256C. MML-1/Mondo regulates lysosome-to-nucleus signaling in gonadal longevity. Oezlem Karalay, Shuhei Nakamura, Makoto Horikawa, Kayo Nakamura, Christian Latza, Rebecca Tharyan, Adam Antebi.

257A. Evaluation of insuin molecules using a primary culture of the C. elegans TJ356 strain. Tsuyoshi Kawano, Takumi Fujimori, Maki Komatsu, Takashi Iwasaki.

258B. S-allyl-L-cysteine increases resistance to environmental stressors, but has no effect on lifespan in Caenorhabditis elegans. Junsung Kim, Sang-Kyu Park.

259C. Ceramide Biosynthesis Impacts Stress Responses in C.elegans- A Model for Mitochondrial Dysfunction. Skylar King, Daniel Quan, Rajeev Azad, Pamela Padilla.

260A. Transgenerational inheritance of hormetic effects in C. elegans. S. Kishimoto, M. Uno, E. Nishida.

261B. Captopril extends lifespan, reduces body fat and improves response to stress in Caenorhabditis elegans. S. Kucuktepe, S. Tegegne, Y. Liu, D. Benheim, B. Xian, J.-D. Han, A. Mechler, W. Grant, M. Jois.

262C. am117 delays somatic and reproductive aging in Caenorhabditis elegans by a mechanism that resembles caloric restriction. Sandeep Kumar, Zuzana Kocsisova, Asa Earnest, Daniel L. Schneider, Kerry Kornfeld.

263A. The interplay between autophagy and the heat shock response in C. elegans. Caroline Kumsta, Jessica Schmalz, Sara Gelino, Jessica Chang, Malene Hansen.

264B. Adiponectin receptors couple protein homeostasis and cellular metabolism to modulate ageing in C. elegans. Emmanouil Kyriakakis, Nektarios Tavernarakis.

265C. Analysis of the Genetic and Cellular Impact of Glucose Supplementation and Oxygen Deprivation in C. elegans. ML Ladage, AM Garcia, PA Padilla.

266A. An in vivo sensor of mitochondrial function in C. elegans for toxicity screening and repositioning of drugs. Cristina Lagido, Debbie McLaggan, L. Anne Glover.

267B. Novel regulators of oxidative stress in C. elegans. Regina Lai, Grace Goh, Stefan Taubert.

268C. Inhibition of DDL-1 selectively regulates a subset of HSF-1 targets. Yi-Chun Lai, Ao-Lin Hsu.

269A. Benefits of physical exercise to healthy aging in C. elegans. Ricardo Laranjeiro, Mizanur Rahman, Daniel Burke, Mary Anne Royal, Christina Chang, Tianyi Yu, Siva A. Vanapalli, Monica Driscoll.

270B. Elucidating a dual role of Wnt signalling pathway in age-regulation in Caenorhabditis elegans. Marco Lezzerini, Yelena Budovskaya.

271C. Functional regulation of the DAF-16/FoxO transcription factor by acetylation in response to stress. Chung-Yi Liang, Xiaokun Yu, Wei-Chung Chiang, Yi-Chun Lai, David B. Lombard, Ao-Lin Hsu.

272A. Functions of CLIC proteins in heat stress in C. elegans. Jun Liang, Cathy Savage-Dunn, Lizette Flores, Keresser Leo, Shani Schreiber.

273B. Mitochondrial Ca2+ uniporter (mcu-1) regulates autophagy and mitochondrial UPR in Caenorhabditis elegans.. Yun-Ki Lim, Choon Kee Min, Dongwook Kim, Moon Kyung Kang, Yeon-Soo Kim, Soo Hyun Eom, Joohong Ahnn, Sun-Kyung Lee, Do Han Kim.

274C. The mitochondrial protein import machinery as a determinant of longevity in C. elegans. Eirini Lionaki, Ilias Gkikas, Nektarios Tavernarakis.

275A. Investigating the conservation of cellular buffering of mild heat stress. Jaime Lisack, Lisa Petrella, Te-Wen Lo.

276B. Role of RPL-11.2 in the Metabolic Response to Starvation Stress. Analyn Lizaso, Chun-Lan Huang, Ying-Hue Lee.

277C. New roles of WDR-23 regulation in oxidative stress response. Jacqueline Lo, Sean Curran.

278A. A metabolomic perspective of the impact of mitochondrial prohibitin on C. elegans longevity. Artur B. Lourenço, Celia Muńoz Jiménez, David Cabrerizo Granados, Mónica Venegas Calerón, Mary Doherty, Phillip Whitfield, Marta Artal-Sanz.

279B. Comparing regulation and function of DAF-16/FOXO in different longevity pathways in C. elegans. Hildegard Mack, James Moresco, John R. Yates, Cynthia Kenyon.

280C. Chronic proteasome dysfunction in C. elegans activates a compensatory response involving skn-1, elt-2, and lysosome activity. Sarah K. Maddux, Scott A. Keith, Yayu Zhong, Annabel A. Ferguson, Arjumand Ghazi, Alfred L. Fisher.

281A. C. elegans high-content screen to identify interventions acting on mitochondria to extend lifespan through neuronal hormesis. Silvia Maglioni, Alfonso Schiavi, Anjumara Shaik, Natascia Ventura.

282B. Oxidative quality control regulates response to ER stress through translation control. Latika Matai, Shuvadeep Maity, Asher Rajkumar, Shantanu Sengupta, Arnab Mukhpadhyay, Kausik Chakraborty.

283C. Dopamine Signaling Regulates Protein Homeostasis Through The Ubiquitin Proteasome Systems. Kishore Joshi, Tarmie Matlack, Christopher Rongo.

284A. Analysis of intergenerational effects of starvation. Shinya Matsumoto, Haruka Saito, Midori Ogai, Mayu Morishita, Megumi Sei, Sawako Okada, Ayano Nishida, Akari Sawanaga, Midori Sakagami, Kosuke Kato, Yasuki Matsumura.

285B. TRX-1 as a potential redox regulator of the major C. elegans oxidative stress transcription factor, SKN-1. Katie McCallum, Bin Liu, Juan Carlos Fierro-González, Peter Swoboda, Swathi Arur, Antonio Miranda-Vizuete, Danielle Garsin.

286C. Mechanisms of animal-to-animal and cell-to-cell variation in gene expression in adult hermaphrodites. Alexander Mendenhall, Bryan Sands, Patricia Tedesco, Thomas Johnson, Roger Brent.

287A. Toward the identification of genetic pathways involved in muscle aging in Caenorahbditis elegans. Adeline Mergoud dit Lamarche, Laurent Molin, Kathrin Gieseler, Jean-Louis Bessereau, Florence Solari.

288B. Dietary restriction involves NAD+-dependent mechanisms and a shift towards oxidative metabolism. Natalie Moroz, Juan Carmona, Edward Anderson, Anne Hart, David Sinclair, Keith Blackwell.

289C. Comparative Analysis of Human Alzheimer’s Risk Factor Genes from GWAS and Linkage Analyses.. Behrad Vahdati Nia, Deborah Lee, Phong Ta, Steven Munassi, Shin Murakami.

290A. Novel effect and mechanism for prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans.. Hisako Nakagawa, Tadaaki Miyazaki.

291B. Exploring the substrate specificity of the C. elegans atypical calpain CLP-1. L. Newman, P. Kuwabara.

292C. Investigating neuronal modulation of stress resistance and aging. K. Obrochta, J. Garrison.

293A. Supplementation of N-acetyl-L-cysteine mimics the effect of dietary restriction on lifespan in Caenorhabditis elegans. Seung-Il Oh, Jin-Kook Park, Sang-Kyu Park.

294B. Dietary restriction promotes healthspan via a glucagon-like signaling pathway in C. elegans. Brian Onken, Monica Driscoll.

295C. Uncovering the mechanisms by which the neurosensory release of serotonin modulates the Heat Shock Response in Caenorhabditis elegans. Felicia Ooi, Veena Prahlad.

296A. DNA damage-induced autophagy and necrotic neurodegeneration during ageing. Margarita Elena Papandreou, Nektarios Tavernarakis.

297B. Deciphering How the Germline Inhibits Longevity. T. Richard Parenteau, Cynthia Kenyon.

298C. Hypoxia and the Mitochondrial Unfolded Protein Response. Salvador Peńa, Teresa Sherman, Paul Brookes, Keith Nehrke.

299A. Elucidating the mechanisms for purifying selection of mitochondrial DNA. Sagen Peterson, Sidhartha Goyal, Yamila Torres Cleuren, Joel Rothman.

300B. Specific microRNAs Regulate Heat Stress Responses in Caenorhabditis elegans. Agnieszka Podolska, Camilla Nehammer, Sebastian D. Mackowiak, Konstantinos Kagias, Roger Pocock.

301C. The G-protein coupled receptor FSHR-1 is required for multiple facets of the innate immune response in C. elegans. Elizabeth Miller, Leah Grandi, Joseph Robinson, Jennifer Giannini, Jennifer Powell.

302A. Modulation of longevity and stress response pathways by SUMOylation in C. elegans. Andrea Princz, Nektarios Tavernarakis.

303B. Role of SEM-4 in BRAP-2/SKN-1/ROS detoxification pathway. Adilya Rafikova, Lesley MacNeil, Marian Walhout, Terrance J. Kubiseski.

304C. A microfluidic platform for parallelized aging and healthspan investigations in C. elegans. Mizanur Rahman, Hunter Edwards, Nikolajs Birze, Jennifer E. Hewitt, Rebecca Gabrilska, Kendra P. Rumbaugh, Jerzy Blawzdziewicz, Nathaniel Szewczyk, Monica Driscoll, Siva A. Vanapalli.

305A. Molecular signatures of reproductive aging in C. elegans. I. Ramanandraitsiory, S. Kumar, F. Borondics, M. Hackett, C. Carvalho, T. Ellis.

306B. Non-cell-autonomous activation of the oxidative stress response by atypical antidepressants extends lifespan of Caenorhabditis elegans. Sunitha Rangaraju, Gregory Solis, Sofia Andersson, Rafael Gomez-Amaro, Rozina Kardakaris, Caroline Broaddus, Alexander Niculescu, Michael Petrascheck.

307C. Investigations on cell- and tissue-specific activity of NER upon UVB irradiation in development and ageing of C. elegans. Matthias Rieckher, Vincent Anton, Amanda Lopes, Paul Werthenbach, Björn Schumacher.

308A. Tissue-specific effects of a solute carrier membrane protein on the regulation of aging. Nina Riehs, Cynthia Kenyon.

309B. The Possible Benefits of Ceratonia siliqua (carob) Fruit Extract in Caenorhabditis elegans. Cristiane Rodrigues, Ana Thalita Soares, Mariani Vasconcellos, Cristiane Denardin, Daiana Ávila.

310C. N-acylethanolamines modulate C. elegans longevity at warm temperatures. Pedro Reis-Rodrigues, Neale Harrison, Matthew S. Gill.

311A. Regulation of insulin signaling by a truncated isoform of the insulin receptor.. Pedro Reis-Rodrigues, Prosenjit Mondal, Aditi Gurkar, Scott T. Baker, Neale Harrison, Brock Grill, Matthew S. Gill.

312B. The loss of mma-1 LRPPRC function induces the mitochondrial unfolded protein response. Fabian Koehler, Kathrin Mueller-Rischart, Barbara Conradt, Stephane Rolland.

313C. Analysis of Nucleotide Excision Repair in vivo. Mariangela Sabatella, Karen Thijssen, Wim Vermeulen, Hannes Lans.

314A. Investigating the Role of Host Cell Factor 1 and Ribosomal S6 Kinase in Regulation of Longevity. Seth Sagulo, Siu Sylvia Lee.

315B. 4-aryl-telluroquinoline improves longevity of stressed Caenorhabditis elegans in a skn-1 dependent manner. Willian Salgueiro, Michael Aschner, Daiana Ávila.

316C. Ubiquitin-and Proteasome-rich Spheres Form in Response to Cellular Stress. Katherine Sampuda.

317A. Ubiquitin localization changes as C. elegans undergo stress. Jacob Sanders, Lynn Boyd.

318B. A novel γ-secretase independent role for presenilin in mitochondrial function and morphology. Shaarika Sarasija, Kenneth Norman.

319C. Stress response pathways are upregulated in long-lived mitochondrial mutants and show differential interaction with aging. Claire Schaar, Jeremy Van Raamsdonk.

320A. Amyloid formation controls worm behavior. Andrea Scharf, Annette Piechulek, Anna von Mikecz.

321B. Iron starvation-induced mitophagy mediates lifespan extension upon mitochondrial stress in C. elegans. Alfonso Schiavi, S. Maglioni, A. Shaik, K. Palikaras, V. Brinkmann, A. Torgovnick, N. Tavernarakis, N. Ventura.

322C. Sphingolipid and Diet Manipulations in the Aging Gut of Caenorhabditis elegans. Dustin Servello, Luke Gangi-Wellman, Abby Nolan, Regina Lamendella, Trisha Staab, Jason Chan.

323A. Applying a Spatial-Temporal Controlled Gene Expression System to Aging Research. Xingyu She, Malene Hansen.

324B. The Role of Neuropeptide Neuromedin U Signaling in the Sensory Influence on C. elegans Physiology via Food-Type Recognition. Deniz Sifoglu, Shashwat Mishra, Roxani Gatsi, Anca Neagu, Wolfgang Maier, Joy Alcedo.

325C. A link between the effects of 4-hydroxynonenal (4-HNE) on fat accumulation and aging. Kevin McElhanon, Kira Bennet, Sharda Singh.

326A. Antiretroviral drugs cause immediate mitochondrial dysfunction, likely prompting mitohormesis, which can be attenuated by antioxidants. Reuben Smith, Stanley Brul, Hans van der Spek.

327B. Ilex paraguariensis reduced fat storage in Caenorhabditis elegans. Marina Machado, Leticia Arantes, Daniele Zamberlan, Tassia da Silveira, Ingrid da Silva, Félix Soares'.

328C. C09F5.1, the BRICHOS containing protein functions in stress resistance. Myung Chul Song, Sung Hee Kim, Kyung Hee Song, Ching Tack Han.

329A. Olfactory Regulation of C. elegans Reproductive Aging. Jessica Sowa, Ayse Sena Mutlu, Meng Wang.

330B. The Effects of Wrapping NGM Culture Plates with Parafilm M® on the Growth and Development of Caenorhabditis elegans. Patrick Spica, Emra Klempic, Sara Scanga, Jessica Shinn-Thomas.

331C. Stress tolerance and lifespan in C. elegans are modulated by natural allelic variation in cmk-1 . Mark G. Sterken, L. Basten Snoek, Roel P. J. Bevers, Rita J. M. Volkers, Arjen Van 't Hof, Rachel Brenchley, Ben Lehner, Andrew Cossins, Jan E. Kammenga.

332A. Slowing Down: Diverse interventions extend C. elegans lifespan through temporal scaling. Nicholas Stroustrup, Winston Anthony, Javier Apfeld, Walter Fontana.

333B. Identifying the metabolic pathways involved in phosphine resistance in alh-6(wr3) mutant . Nisa Suraj Nath, Paul R. Ebert.

334C. Inhibition of HSB-1 induces an altered HSF-1 transactivation profile to promote longevity. Surojit Sural, Carol Mousigian, Ao-Lin Hsu.

335A. Role of aggregation-prone proteins in age-related disease. Pooja Suri, Meenakshisundaram Balasubramaniam, Ramani Alla, Robert Shmookler Reis, Srinivas Ayyadevara.

336B. Ionizing radiation and oxidative stress suppress locomotion and pharyngeal pumping motion in Caenorhabditis elegans. M. Suzuki, T. Sakashita, Y. Hattori, Y. Kobayashi.

337C. Oxidative stress response of a transcription factor MXL-3 in the nematode C. elegans. Kodai Takahashi, Kayo Yasuda, Takamasa Ishii, Noboru Sasagawa, Phil Hartman, Naoaki Ishii.

338A. Disruption of a specific cuticle structure activates cellular detoxification and osmotic stress response genes implicating the presence of an environmental stress sensor in the extracellular barrier. Lanlan Tang, Will Dodd, Keith Choe.

339B. Long live the queen: Apis royalactin extends life and improves health in C. elegans. Giel Detienne, Wouter De Haes, Ulrich R. Ernst, Liliane Schoofs, Liesbet Temmerman.

340C. PRDX-2 mediates lifespan extension by metformin. Wouter De Haes, Geert Depuydt, Lotte Frooninckx, Roel Van Assche, Arne Smolders, Johan Billen, Bart P. Braeckman, Liliane Schoofs, Liesbet Temmerman.

341A. Mitochondrial Regulation in C. elegans Adult Reproductive Diapause. R. Tharyan, B. Gerisch, A. Antebi.

342B. Genetic Analysis of Endoplasmic Reticulum Homeostasis and Tolerance to Infection in C. elegans. Erik Tillman, Douglas Cattie, Claire Richardson, Kirthi Reddy, Dennis Kim.

343C. C. elegans PERK ortholog, pek-1, is responsible for the rapid phosphorylating eIF2α upon heat shock. Robert Todd, Veena Prahlad.

344A. Novel gene interactions that modulate morphological aging of neurons in C. elegans. Marton Toth, Ivana Ganihong, Kelli Gaul, Khushboo Patel, Ryan Guasp, Girish Harinath, Wenying Zhang, Jian Xue, Monica Driscoll.

345B. How does the Hexosamine Pathway regulate Protein Quality Control and Longevity? Sarah I. Tremmel, Adam Antebi.

346C. The SKN-1/Nrf2 transcription factor protects against oxidative damage and promotes longevity in C. elegans by distinct mechanisms. Jennifer Tullet, Catherine Au, Emily Clarke, Adelaide Young, David Gems.

347A. NHR-49 Coordination of Fatty Acid Metabolism is Required for Healthy Mitochondrial Structure/Function and Hypoxia Sensitivity. Marc R. Van Gilst, Pranali Pathare, Michael Crowder.

348B. The complex relationship between reactive oxygen species and aging: levels and location determine the effect of superoxide on lifespan. Jeremy Van Raamsdonk, Claire Schaar, Dylan Dues, Katie Spielbauer, Emily Machiela, Jason Cooper, Megan Senchuk.

349C. Protein homeostasis dysregulation is associated with aberrant morphology and reduced function of aging mechanosensory neurons. Elena Vayndorf, Courtney Scerbak, Skyler Hunter, Marton Toth, J. Alex Parker, Christian Neri, Monica Driscoll, Barbara Taylor.

350A. Proteostasis imbalances impact sensory and motor neuron function in C. elegans animals expressing TDP-43. Quan Nguyen, Emily Rendleman, Zelene Figueroa, Cindy Voisine.

351B. A C.elegans RNAi screen identifies novel genes with antagonistic pleiotropic effects. Thomas Wilhelm, Jonathan Byrne, Rebeca Medina, Holger Richly.

352C. Identifying novel regulators of endoplasmic reticulum redox. Alan Winter, Antony Page.

353A. Investigating the Role of Homeodomain-Interacting Protein Kinase (HPK-1) in Caenorhabditis elegans. Mallory Wood, Slavica Berber, Priya Thaivalappil, Hannah Nicholas.

354B. The Skp1 homologs SKR-1/2 regulate the SKN-1/Nrf antioxidant and detoxification response via a non-cononical mechanism independent of p38 MAPK. Cheng-Wei Wu, Andrew Deonarine, Keith Choe.

355C. mTORC2 and neuroendocrine signaling modulate C. elegans physiology and aging in a diet-dependent manner. Rui Xiao, Lei Chun, Elizabeth Ronan, David Friedman, Jianfeng Liu, X. Z. Shawn Xu.

356A. Detection and measurement of abnormal posture under stressful conditions in age-related mutants . S. Matsuda, N. Nitta, M. Tamura, M. Suzuki, T. Sakashita, N. Ishii, S. Yanase.

357B. Rosmarinus officinalis L. extends Caernohabditis elegans longevity in a DAF-16, SKN-1 and HSF-1 dependent way. D. Zamberlan, L. Arantes, G. Amaral, M. Machado, F. Soares.

358C. Multigene analysis of aging markers in Caenorhabditis elegans using directed evolution. Yuehui Zhao, Kathy Bates, Charles Zhao, Hang Lu, Patrick McGrath.

359A. Profiling the aging proteome in C. elegans reveals a new role for extracellular uterine proteins in aging. Stephanie Zimmerman, Izumi Hinkson, Joshua Elias, Stuart Kim.

Physiology - Dauer Larvae and Metabolism

360B. Pharynx remodeling and suppression of pharyngeal activity in C. elegans dauer larvae. Ulkar Aghayeva, Oliver Hobert.

361C. Ascaroside biosynthesis in C. elegans. Allison Akagi, Oishika Panda, Joshua Judkins, Frank Schroeder, Paul Sternberg.

362A. Sucrose and Artificial Sweeteners Affect C. elegans Fertility and Body Fat Content. Sofia N. Allison, Kristine E. Jones, Katherine M. Walstrom.

363B. Role of autophagy in IL2 dendritic arbors during dauer formation and recovery. Rebecca J. Androwski, Kristen M. Flatt, Nathan E. Schroeder.

364C. Gene regulatory networks that mediate responses to different bacterial diets. Jote T. Bulcha, Gabrielle Giese, Albertha J. M. Walhout.

365A. Excretory-secretory products (ESP) profiling of Caenorhabditis elegans provide clues for environmental and developmental regulation. Wen Chen, Paul Sternberg.

366B. Spinal Muscular Atrophy (SMA) Genes Regulate Insulin Signaling in Response to High-Glucose Diet. Kevin Deehan, Michael Mastroianni, Emma Sikes, John Hanover, Michael Krause, Michelle Mondoux.

367C. The histone H4K20 methyltransferase SET-4 promotes dauer arrest in C. elegans insulin signaling mutants. Colin Delaney, Kathleen Dumas, Jacqueline Graniel, Stephan Flibotte, Donald Moerman, Patrick Hu.

368A. Epoxides derived from a specific dietary polyunsaturated fatty acid induces germ cell death in C. elegans. Marshall Deline, Julia Keller, Michael Rothe, Wolf-Hagen Schunck, Ralph Menzel, Jennifer Watts.

369B. Nuclear hormone receptor NHR-28 interacts with the insulin signaling pathway and the TGF-β pathway in dauer formation. Grace Y. S. Goh, Stefan Taubert.

370C. Regulation of fat and body growth by SIKs and class II HDACs. Jeremy Grubbs, Ari Winbush, Alexander van der Linden.

371A. Small molecule mediated nuclear receptor DAF-12 signaling regulates development and lifespan in C. elegans. Pooja Gudibanda, Andreas Ludewig, Parag Mahanti, Axel Bethke, Frank Schroeder.

372B. Regulation of gluconeogenesis and its role in attenuating excitability of the male mating circuitry. Xiaoyan Guo, Luis Rene Garcia.

373C. Metabolic profiling and metabolic flux analyses in NAD+ salvage biosynthesis mutants. Wenqing Wang, Melanie McReynolds, Jimmy Goncalves, Muya Shu, Ineke Dhondt, Bart Braeckman, Stephanie Lange, Kelvin Kho, Ariana Detwiler, Marisa Pacella, Wendy Hanna-Rose.

374A. Investigating the pathway through which gpa-3 controls fat metabolism in C. elegans. Rosalind Hussey, Tiffany Locke, Jonathan Stieglitz, Supriya Srinivasan.

375B. Springing the worm trap: the signal sequence receptor ortholog TRAP-1 regulates DAF-2 insulin-like signaling. Omar Itani, Kathleen Dumas, Stephane Flibotte, Donald Moerman, Patrick Hu.

376C. Disrupting BCKDH in Caenorhabditis elegans leads to multiple developmental defects which are mainly caused by mmBCFA deficiency but not BCAA accumulation. F. Jia, M. Cui, M. Than, M. Han.

377A. The influence of dietary bacteria genotypes on dauer formation in C. elegans. A. Khanna, J. Kumar, M. Vargas, S. Katewa, T. McCloskey, M. Gill, P. Kapahi.

378B. Influence of dietary and environmental variations on C. elegans development. Lucie Kozlowski, Alberta J. M. Walhout.

379C. The heterochronic transcription factor lin-14 promotes dauer arrest. Joseph Kruempel, Albert Chen, Stephane Flibotte, Donald Moerman, Patrick Hu.

380A. Characterization of Mechanisms of Dauer Entry Triggered by Neuronal Unfolded Protein Response (UPR) Activation. Warakorn Kulalert, Dennis H. Kim.

381B. The majority of C. elegans FLP genes increase expression around the dauer diapause commitment decision. James Lee, Pei-Yin Shih, Oren Schaedel, Alicia Rogers, Igor Antoshechkin, Paul Sternberg.

382C. Cytoplasmic-Specific NAD+ Deficiency Disrupts Glycolysis and Activates Amino Acid Catabolism Affecting Reproductive Development in C. elegans. Melanie McReynolds, Wendy Hanna-Rose.

383A. Maintaining Global NAD+ Homeostasis Reveals Separable Functional and Compensatory Roles for NAD+ Biosynthetic Pathways in C. elegans. Melanie McReynolds, Wenqing Wang, Wendy Hanna-Rose.

384B. Bis(2-ethylhexyl) phthalate as a toxic developmental regulator of sterol metabolism in C. elegans . Santanu Mukherjee, Tanaya Paul, Jaya Bandyopadhyay.

385C. Fluorescent beads are a versatile tool to distinguish dauer larvae and other stages. Liberta Nika, Taylor Gibson, Rebecca Konkus, Xantha Karp.

386A. Bipolar worms with a metastable metabolome. Oishika Panda, Joshua Judkins, Allison Akagi, Paul Sternberg, Frank Schroeder.

387B. Deficiency in peroxisomal fatty acid metabolism causes abnormalities in Insulin/IGF-1 signaling and ER homeostasis, leading to an altered life history in Caenorhabditis elegans. Saeram Park, Hyoe-Jin Joo, Young-Ki Paik.

388C. Depletion of lipid stores and inhibition of RNA polymerase III by constitutively activated MAFR-1 . Akshat Khanna, Ajay Pradhan, Andres Ixtlahuac, Meagan He, Sean Curran.

389A. A novel circuit coordinating mevalonate pathway metabolism with mitochondrial stress . Amir Sapir.

390B. A lipid-TORC1 pathway promotes neuronal development and foraging behavior in C. elegans. Marina Kniazeva, Huanhu Zhu, Aileen K. Sewell, Kelley Anderson, Min Han.

391C. The development of dauer commitment markers for decision-dynamics studies. Pei-Yin Shih, James Lee, Paul Sternberg.

392A. Nicotinamide mononucleotide adenylyltransferase function in C. elegans. Muya Shu, Wendy Hanna-Rose.

393B. The role of autophagy genes in lipid homeostasis. Melissa J. Silvestrini, Hannah Hong, Alicia Melendez.

394C. Glucose intolerance during C. elegans embryogenesis. Jeffrey Simske, Yi Dong.

395A. Male hypersensitivity to dauer entry: a model for sex differences in larval physiology. Hannah Steinert, Douglas Portman.

396B. s-adenosylmethione levels govern innate immunity through distinct methylation-dependent pathways . Wei Ding, Lorissa Smulan, Noemie Bozonnet, Nicole Hou, Stefan Taubert, Jennifer Watts, Amy Walker.

397C. lpin-1 is necessary for low-PC activation of SBP-1/SREBP-1. Lorissa Smulan, Noemie Bozonnet, Amy Walker.

398A. Expression and function comparison of two AMPK α subunits in C. elegans. L. Yao, G. Zhou, Q. Jin, Y. Wang.

399B. The nuclear receptor DAF-12 regulates nutrient metabolism and reproductive growth in nematodes. Zhu Wang, Jonathan Stoltzfus, Young-jai You, Najju Ranjit, Hao Tang, Yang Xie, James Lok, David Mangelsdorf, Steven Kliewer.

400C. G-protein mediated neuronal oxygen-sensing regulates distal body fat in C. elegans. Emily Witham, Claudio Comunian, Harkaranveer Ratanpal, Supriya Srinivasan.

401A. Chromophore-assisted light inactivation of mitochondrial respiratory chain complex II in C. elegans using a miniSOG mev-1 fusion. Andrew Wojtovich, Teresa Sherman, Thomas Foster, Paul Brookes, Keith Nehrke.

402B. Structural and functional characterization of acyl-CoA oxidases in the ascaroside biosynthetic pathway. Xinxing Zhang, Likui Feng, Kunhua Li, Satya Chinta, Prashant Singh, Yuting Wang, Joshawna Nunnery, Steven Bruner, Rebecca Butcher.

Physiology - Novel Technologies

403C. Quantitative assessment of C. elegans fat levels using dark field microscopy. Anthony Fouad, Kevin Zhang, Moyu Fu, David Raizen, Christopher Fang-Yen.

404A. Real-time behavioral study of C. elegans by dynamic in situ photopatterning of hydrogel assays. Eleni Gourgou*, C. Ryan Oliver*, Daphne Bazopoulou, Nikos Chronis, A. John Hart.

405B. Caenorhabditis Sieve: A novel mechanical approach to sorting C. elegans and other nematode species for age-synchronized, large scale assays. Skyler Hunter, Courtney Scherbak, Elena Vayndorf, Barbara Taylor.

406C. Near-infrared irradiation increases growth rate and brood size. Daryl Hurd, Olivia Edens, Michael Spoto, Max Myakishev-Rempel.

407A. C. elegans as robust, high throughput in vivo system for hazard assessment. Engelien Kerkhof, Christien Lokman, Raymond Pieters, Marjolein Wildwater.

408B. Neurochip: a microfluidic device for improved throughput to translate agrochemical, pharmacological and biological potential of nematode pharyngeal function.. Vincent O'Connor, Fernando Callahorro, James Dillon, Teressa Ferreiro, Lindy Holden-Dye, Hywel Morgan, Chunxiao Hu.

409C. Dissection of the temperature control of C. elegans larval development using a novel high-throughput method. Maria Olmedo, Mirjam Geibel, Marta Artal-Sanz, Martha Merrow.

410A. A Simple Culture System for Long-Term Imaging of Individual C. elegans. Will Pittman, Willie Zhang, Zach Pincus.

411B. Automated scanner-based high throughput phenotype scoring for C. elegans. Timothy Puckering.

412C. Real-time tracking and optical manipulation: Single-cell perturbations in the embryo of Caenorhabditis elegans. Pavak Shah, Anthony Santella, Zhirong Bao.

Physiology - Pathogenesis

413A. The excreted-secreted proteome of C. elegans. Veronica Arinze, Juliana Sacoman, Dylan Rahe, Christopher Weatherly, Patricia Berninsone.

414B. Targeting mitochondria in muscular dystrophies through acting on ROS, mitohormesis and programmed cell death pathways . Mathieu Baritaud, Marie-Christine Mariol, Edwige Martin, Laura Pierson, Bénédicte Chazaud, Carole Kretz-Remy, Ludivine Walter, Kathrin Gieseler.

415C. Phosphorylcholine-modified glycoproteins involved in host immune modulation by parasitic nematodes: a chemical biology approach developed in C. elegans . Casey Snodgrass, Amanda Burnham-Marusich, John Meteer, Patricia Berninsone.

416A. Virulence of a Novel Melanin Producing Pseudomonas Species UC17F4 on Caenorhabditis elegans. Mary Brockett, Meghan Morreale, Jessica Shinn-Thomas, Lawrence Aaronson.

417B. Caenorhabditis elegans is a useful model for anthelmintic discovery. Andrew R. Burns, Genna M. Luciani, Gabriel Musso, Rachel Bagg, May Yeo, Yuqian Zhang, Luckshika Rajendran, John Glavin, Robert Hunter, Elizabeth Redman, Susan Stasiuk, Michael Schertzberg, Sean R. Cutler, Mike Tyers, Guri Giaever, Corey Nislow, Andrew G. Fraser, Calum A. MacRae, John Gilleard, Peter J. Roy.

418C. Whole-animal chemical screen for immune activators identifies molecules that target the nervous system. Xiou Cao, Yun Cai, Alejandro Aballay.

419A. Exploring novel antiviral immunity in C. elegans. Kevin Chen, Carl Franz, Hongbing Jiang, Guang Wu, Hilary Renshaw, David Wang.

420B. Return to the death star: Coryneform bacteria as pathogens of C. elegans. Laura Clark, Camila Azevedo Antunes, Ana Luiza Mattos-Guaraldi, Andreas Burkovski, Jonathan Hodgkin.

421C. Host Mad-Max signaling regulates intracellular pathogen growth. Lianne Cohen, Michael Botts, Chris Probert, Fengting Wu, Emily Troemel.

422A. A role for elt-2 in regulating highly specific immune responses in C. elegans. Katja Dierking, Alejandra Zarate-Potes, Wentao Yang, Hinrich Schulenburg.

423B. Neural regulation of innate immune response using optogenetics. Argenia Doss, Alejandro Aballay.

424C. ML358, a small molecule inhibitor of SKN-1 dependent detoxification genes, sensitizes C. elegans to oxidative stress and anthelmintics. Pauline Fontaine, Yiva Wang, David Leung, Mahesh Peddibhotla, Patrick Maloney, Paul Hershberger, Siobhan Malany, Keith Choe.

425A. C. elegans responds to challenge with bacterial pathogen by production of an invertebrate lysozyme in the intestine and coelomocytes. Maria Gravato-Nobre, Ronald Chalmers, Jonathan Hodgkin.

426B. The role of GATA and other cell-autonomous transcription factors in mediating C. elegans recovery from acute pathogenic infection. Brian Head, Alejandro Aballay.

427C. A paradigm for studying anthelmintic combinations in vivo. Y. Hu, T. Nguyen, M. Miller, R. Aroian.

428A. Assessing the pathogenicity of Orsay virus capsid proteins using PROFECE. Ombeline Hueber, Michelle Mony, Alex Bykov, Frederic Pio.

429B. Genome-wide screen identifies genes involved in gut immunity and homeostasis in C. elegans. Sakthimala Jagadeesan, Abdul Hakkim, Aniqa Osmani, Sid Ahmed Labed, Nidha Ismail, Fred Ausubel.

430C. High-Throughput Screening (HTS) assay for the discovery of anti-infective agents against Acinetobacter baumannii infection. Elamparithi Jayamani, Rajmohan Rajamuthiah, Jonah Larkins-Ford, Beth Burgwyn Fuchs, Annie L. Conery, Andreas Vilcinskas, Frederick M. Ausubel, Eleftherios Mylonakis.

431A. Mitochondrial chaperone HSP-60 confers the anti-bacterial immunity via upregulating PMK-1 signaling in C. elegans. Dae-Eun Jeong, Dongyeop Lee, Sun-Young Hwang, Yujin Lee, Mihwa Seo, Wooseon Hwang, Keunhee Seo, Ara B. Hwang, Murat Artan, Heehwa G. Son, Haeshim Baek, Young-Min Oh, Joo-Yeon Yoo, Seung-Jae V. Lee.

432B. Mitochondrial proteostatic failure with hypoxiaMitochondrial proteostatic failure with hypoxia. Daniel Kaufman, C. Michael Crowder.

433C. A forward genetic screen for host factors involved in enterohemorrhagic E. coli colonization in Caenorhabditis elegans. Cheng-Ju Kuo, Fang-Jung Yang, Chang-Shi Chen.

434A. Pilot studies to determine if dietary polyunsaturated fatty acids cause sterility in plant-parasitic nematodes. E. M. Larson, L. J. Davies, P. T. Y. Dinh, A. A. Elling, J. L. Watts.

435B. Using stress assays to define aberrant neuronal signaling in a C. elegans model of TDP-43 proteinopathy. Nicole Liachko, John Kushleika, Thomas Bird, Brian Kraemer.

436C. Using C. elegans as a primary anthelmintic screening tool. Nicole Liachko, John Kushleika, Aleen Saxton, Brian Kraemer.

437A. Characterization of C. elegans infection by three related microsporidia species. Robert Luallen, Gaotian Zhang, Kirthi Reddy, Marie-Anne Félix, Emily Troemel.

438B. Natural genetic variation in Caenorhabditis elegans response to bacterial pathogens. Natalia Martin, Alejandro Aballay.

439C. Investigating the mechanism of action for the anthelmintic activity of CL-5. Jennifer Miskowski, Mary Sagstetter, Kiersten Brown, Aaron Monte.

440A. Using bacterial pathogens to explore the nematode surface coat. Delia O'Rourke, Dave Stroud, Jonathan Hodgkin.

441B. The role of C-type lectin-like domain proteins in C. elegans immunity. Barbara Pees, Anke Kloock, Hinrich Schulenburg, Katja Dierking.

442C. In vivo identification of host-exposed proteins from microsporidia, a natural intracellular pathogen of C. elegans . Aaron Reinke, Eric Bennett, Emily Troemel.

443A. Mechanisms of nickel toxicity in animals. David Rudel, John Atkinson, Halbert Campbell, Ian Huffnagle, Alyssa Joyner, Blake Rumble, Eli Hvastkovs.

444B. Screening and identification of Photorhabdus luminescens virulence-related genes using C. elegans as a model host. Kazuki Sato, Toyoshi Yoshiga, Koichi Hasegawa.

445C. A C. elegans genome-wide RNAi screen identifies modifiers of mutant TDP-43. Aleen Saxton, Nicole Liachko, Brian Kraemer.

446A. Chronic exposure to pesticide residues exacerbates α-synuclein pathology in a Caenorhabditis elegans Parkinson’s disease model. A. Schlosser, M. Davis, D. Flaherty.

447B. Exploring the role of axon guidance molecules in pancreatic cancer using C. elegans. Holly Sucharski, Morgan Gardner, Seth Coombs, Axucillia Kagande, Rodney Nichols, Jamie Alan.

448C. Characterization of a novel C. elegans Alzheimer’s model with constitutive neuronal expression of Aβ1-42. E. Teo, S. Fong, L. Ng, S. Tsoi, L. Lakshmanan, C. Chen, B. Halliwell, J. Gruber.

449A. The bacterial secondary metabolite violacein affects C. elegans development, fecundity and behavior. Kyoung-hye Yoon, Seong Yeol Choi, Robert J. Mitchell, Jin Il Lee.

450B. Genetic analysis of the role of the GATA transcription factor ELT-2 in the strain-specific interaction with the natural pathogen Bacillus thuringiensis . A. Zarate Potes, W. Yang, R. Schalkowski, H. Schulenburg, K. Dierking.

451C. Characterization of nematode-infecting microsporidia and natural variation in sensitivity of Caenorhabditis nematodes to microsporidia. Gaotian Zhang, Marie-Anne Felix.

Neurobiology - Behavior

452A. Identification of neuronal targets of Insulin/FOXO signaling reveals novel components required for associative learning and memory formation. Rachel Arey, Rachel Kaletsky, Vanisha Lakhina, April Williams, Jessica Landis, Amanda Kauffman, Geneva Stein, Coleen Murphy.

453B. Vitamin B3/Nicotinamide is an agonist for OSM-9/OCR-4 TRPV ion channel in Caenorhabditis elegans. A. Upadhyay, M. Crook, T. Jegla, W. Hanna-Rose.

454C. Developing a worm model to study chronic effects of the selective serotonin reuptake inhibitor, escitalopram on behavior. Tykayah Baird, Maria Niemuth, Lucinda Carnell.

455A. Large-scale deorphanization of C. elegans neuropeptide receptors. Isabel Beets, Jelle Caers, Esra Baytemur, Elien Van Sinay, Katleen Peymen, Jan Watteyne, Liliane Schoofs.

456B. Determining the function of long-chain polyunsaturated fatty acids in the behavioral response to ethanol. Ryan Hayden, Laura Mathies, Andrew Davies, Bettinger Jill.

457C. Tolerance to a cholinergic activating effect of alcohol requires a specific function of the EAT-6 Na+/K+-ATPase. E. G. Hawkins, I. Martin, L. M. Kondo, J. C. Bettinger, A. G. Davies.

458A. Serotonin promotes exploitation in complex environments by accelerating decision-making.. Shachar Iwanir, Adam Brown, Stanislav Nagy, Dana Najjar, David Biron.

459B. Compressibility quantifies the stereotypy and complexity of C. elegans locomotion. Alex Gomez-Marin, Greg Stephens, Andre Brown.

460C. Caenorhabditis elegans Piezo Ortholog Expression. Katherine Brugman, Paul Sternberg.

461A. NPR-9, a galanin-like G-protein coupled receptor, and GLR-1 regulate interneuronal circuitry underlying locomotory responses. Jason Campbell, Ian Chin-Sang, William Bendena.

462B. The touch receptor neuron mechanotransduction complex is aMEC-42MEC-10 trimer. Yushu Chen, Shashank Bharill, Ehud Isacoff, Martin Chalfie.

463C. Investigation of C. elegans Durotaxis Shows Localization to High Rigidity Substrates. S. Cheng, G. Trusz, K. Arisaka.

464A. The male-specific CEM neurons sense sex pheromone via Go-mediated signaling in C. elegans. Ching-Ki Li, King-Lau Chow.

465B. Neural circuits involved in octopamine succinylated ascaroside #9 mediated avoidance responses. Christopher Chute, Jagan Srinivasan.

466C. Monoamines differentially modulate the release of subsets of neuropeptides from the ASI sensory neurons. Vera Hapiak, Tobias Clark, Amanda Ortega, Richard Komuniecki.

467A. Nonlinear sensory integration in C. elegans: a computational model. Tom Sanders, D. D. Ghosh, M. N. Nitabach, Netta Cohen.

468B. Taurine is a cholinergic antagonist of the C. elegans male mating circuit. Paola Correa, Luis Rene Garcia.

469C. Ultraviolet light induces behavioral quiescence. Hilary K. DeBardeleben, David M. Raizen.

470A. Mate or Resist: effect of self-fertility on reproductive choice behavior. Alexandra Ding, Adam Bahrami, Christopher Fang-Yen, Yun Zhang.

471B. Dopamine induces circling locomotion in C. elegans. Tyson Edwards, Bicheng Han, Jihong Bai.

472C. C. elegans Model of Amyotrophic Lateral Sclerosis: Understanding the Role of TDP-43 Expression on HSN Motor Neuron Function. Zelene Figueroa, Cindy Voisine.

473A. The germline growth affects the neuronal circuits and the behavioral patterns of worms. Manabi Fujiwara, Itaru Aoyama, Shinichi Maruyama, Takeshi Ishihara.

474B. Host-seeking strategies of skin-penetrating parasitic nematodes. Spencer Gang, Michelle Castelletto, Arezoo Barnia, Ryo Okubo, Anastassia Tselikova, Elissa Hallem.

475C. Neuroendocrine reinforcement of a dynamic multisensory decision. D. D. Ghosh, T. Sanders, S. Hong, D. L. Chase, N. Cohen, M. R. Koelle, M. N. Nitabach.

476A. RPM-1, a key regulator of neuronal development, functions in C. elegans behavior. Andrew Giles, Karla Opperman, Catharine Rankin, Brock Grill.

477B. The neuronal basis of bacterial food odor preference. Kevin Chung, Lillian Haynes, Emily Kan, Ryan Ota, Melissa Chambers, Elizabeth Glater.

478C. How do specific shifts in fuel utilization mediate the cell excitability of neurons and muscles in Caenorhabditis elegans behavioral circuits? Jimmy F. Goncalves, L. Rene Garcia.

479A. Magnetic field effects on C. elegans locomotive behavior. Eleni Gourgou, Ehsan Mirzakhalili, Bogdan Epureanu.

480B. Purine biosynthetic intermediates are toxic to the neuromuscular system. Wenqing Wang, Haley Janowitz, Renetta Trotman, Laura Rohan, Sarah D'Souza, Wendy Hanna-Rose.

481C. AFD-mediated thermosensory signal transduction and circuit function in Caenorhabditis elegans . Vera Hapiak, Piali Sengupta.

482A. How do worms choose the right foods? Genes and circuits that drive olfactory dependent sensori-motor behaviors. Gareth Harris, Yun Zhang.

483B. A Roaming-Dwelling Axis Dominates Variation in Motile Behavior Across Nematode Species. Stephen Helms, Antonio Carlos-Costa, Leon Avery, Greg Stephens, Tom Shimizu.

484C. Sexually-dimorphic Expression of a C. elegans Neuromodulator and Its Role in Behavior. Zoe Hilbert, Dennis Kim.

485A. ADAM17/TACE homolog ADM-4 mediates stress-induced quiescence in C. elegans. Andrew Hill, Danna Gal, Cheryl Van Buskirk.

486B. Odor preference is changed over development in C. elegans. T. Hino, M. Fujiwara, T. Ishihara.

487C. TRAMS: A system for three-dimensional tracking of behaviour. Robert Holbrook, Netta Cohen.

488A. Transcription factor lin-32 is essential for synaptogenesis in AIB interneuron, sustained neck muscle contraction and aversive behavior. S. Hori, S. Oda, Y. Suehiro, Y. Iino, S. Mitani.

489B. Fatal attraction: The olfactory neurons AWCs of Caenorhabditis elegans mediate attraction toward nematophagous fungus Arthrobotrys oligospora. Yen-Ping Hsueh, Matthew R. Gronquist, Erich M. Schwarz, Ravi D. Nath, Frank C. Schroeder, Paul W. Sternberg.

490C. A new multi-worm tracker reveals unprecedented insights on worm chemotaxis. Eyal Itskovits, Alon Zaslaver.

491A. A high-throughput screening approach using model organisms for Niemann-Pick Type C disease. Sangeetha Iyer, Nina DiPrimio, Tom Hartl, Kiran Singh, Alec Ludin, Tamy Portillo, Ethan Perlstein.

492B. Activation of SEB-3 in LUA interneurons potentiates male mating drive of C. elegans. Changhoon Jee, Brigitte LeBoeuf, L. René García.

493C. AIY, a one neuron locus for sensorimotor integration. Ni Ji, Vivek Venkatachalam, Maria Lim, Taizo Kawano, Christopher Clark, Hillary Rodgers, Mark Alkema, Mei Zhen, Aravinthan Samuel.

494A. Sensorimotor signal transmission through AIY interneuron in Caenorhabditis elegans during isothermal tracking. Karen Jiang, Steve Mendoza, Nathaniel Nowak, Leonard Haller, Linsay Ling, Tim Sherry, Katsushi Arisaka.

495B. GPA-9, a G-protein alpha subunit, regulates a food preference decision. Konstantinos Kagias, Gareth Harris, Myung-kyu Choi, He Liu, Yun Zhang.

496C. Attractors in Velocity Space During 2D Navigation of C. elegans. M. Kao, T. Kim, D. Woolfork, B. Lam, K. Jiang, N. Nowak, S. Mendoza, K. Arisaka.

497A. Economic decision-making and neural correlates of value in C. elegans. Abraham Katzen, William Harbaugh, Shawn Lockery.

498B. Analysis of downstream regulatory components of the TIR-1/JNK-1 pathway for forgetting of the olfactory adaptation in C. elegans. T. Kitazono, S. Higaki, A. Inoue, T. Ishihara.

499C. Loss of tax-4 function alters the temperature-dependence of egg-laying. Samuel Lasse, Diana Koulechova, Miriam Goodman.

500A. Age-related neuronal changes. Anagha Kulkarni, Claire Benard.

501B. Antagonistic function of HPL-2 and SET-2 in olfactory adaptation of the AWC neuron. Yu-Lin Kuo, Bi-Tzen Juang.

502C. Identification and characterization of new genes involved in Dopaminergic neurons function by cell specific knock-down. A. Lanzo, L. Pannone, M. Tartaglia, P. Bazzicalupo, S. Martinelli, B. Safratowich, L. Carvelli, E. Di Schiavi.

503A. Acute food deprivation activates neuropeptide signaling in diverse tissues to modify avoidance behavior. Hiu Lau, Sreekanth Chalasani.

504B. Heterologous Expression in Remodeled C. elegans: A Platform for Monoaminergic Agonist Identification and Anthelmintic Screening. Wenjing Law, Leah Wuescher, Amanda Ortega, Vera Hapial, Patricia Komuniecki, Richard Komuniecki.

505C. Investigation of the EGL-2/EAG K+ channel PAS domain’s role in responding to environmental changes. Brigitte LeBoeuf, Jimmy Gonclaves, L. Rene Garcia.

506A. Temperature-dependent changes in host-seeking behavior in entomopathogenic nematodes. Joon Ha Lee, Elissa Hallem.

507B. Serotonin-dependent Pulse-Width-Modulation control of food uptake. Kyung Suk Lee, Shachar Iwanir, Ronen Kopito, David Biron, Erel Levine.

508C. Regulator of Calcineurin (RCAN-1) in AFD neurons regulates thermotaxis behavior. Weixun Li, Harold Bell, Joohong Ahnn, Sun-Kyung Lee.

509A. The impact of Sleep and sleep deprivation on learning and memory in C. elegans. Yu Yong, Yuanyuan Wu, Fen Zhang, Xiaofei Xia, Wei Li.

510B. Behavioral Adaptation for Dauer Recovery. Daisy S. Lim, Myung Kyu Choi, Junho Lee.

511C. Histone Methylation as a Putative Mechanism of Behavioral Alcohol Tolerance in C. elegans. C. Lin, J. Shih, A. Huang, A. Sunthoram, C. Rankin.

512A. Long-term olfactory associative memory induction by optogenetic stimulation of ASH neuron. Viktoras Lisicovas, Ichiro Maruyama.

513B. Existence of a nematode alarm pheromone. Z. Liu, B. Aleman-Meza, J. Nguyen, S. Jung, W. Zhong.

514C. A redundant neural circuit drives C. elegans responses to social cues. Zheng Liu, Ada Tong, Sarah Leinwand, Kevin Curran, Christopher Chute, Jagan Srinivasan, Sreekanth Chalasani.

515A. Probing the viscoelasticity of the C. elegans body. Frederic Loizeau, Sylvia Fechner, Eileen Mazzochette, Adam Nekimken, Massimo Vergassola, Miriam Goodman, Beth Pruitt.

516B. Molecular and neural analyses of C. elegans avoidance behavior to the plant stress hormone methyl salicylate. Jintao Luo, Long Ma.

517C. Disruption of cellular proteostasis drives sleep behavior in C. elegans. R. Mansfield, C. Van Buskirk.

518A. SWI/SNF chromatin remodeling regulates alcohol-response behaviors. L. D. Mathies, G. G. Blackwell, A. G. Davies, J. C. Bettinger.

519B. Food status regulates three behavioral states in Caenorhabditis elegans. Richard McCloskey, Christopher Fang-Yen.

520C. A glycine receptor subunit homologue, AVR-14, alters short-term memory in an interstimulus interval-dependant manner in C. elegans. . Troy McDiarmid, Evan Ardiel, Catharine Rankin.

521A. Genetic Polymorphisms and the Relationship Between Ambient Temperature and Behavioral Performance in Caenorhabditis elegans. Samuel Lasse, Kevin P. McPherson, Victoria Hoelscher, Erik C. Andersen, Miriam B. Goodman.

522B. Genetic Analysis of Neuronal Signaling Coupling Microbial Detection to the Induction of TGF-β/DAF-7 Gene Expression in C. elegans. Joshua Meisel, Dennis Kim.

523C. The C. elegans MAST Kinase Acts through Stomatin to Regulate Thermotaxis Behavior. Shunji Nakano, Andrew C. Giles, Muneki Ikeda, Takamasa Suzuki, Ayana Sano, Tetsuya Higashiyama, Ikue Mori.

524A. Understanding how sex modulates the female nervous system to drive distinct reproductive behavior states. Layla Nassar, Addys Bode, Kevin Collins.

525B. The force of touch: How gentle is the classical gentle touch assay? Adam L. Nekimken, Eileen A. Mazzochette, Miriam B. Goodman, Beth L. Pruitt.

526C. Uncovering Novel Genes with Neuronal Function Among Human 21st Chromosome Orthologs. S. K. Nordquist, A. M. Griffith, J. T. Pierce-Shimomura.

527A. Uncovering cannabinoid signaling in C. elegans, a new model to study the effects of medical Cannabis sativa. Mitchell Oakes, Wen Jing Law, Amanda Ortega, Richard Komuniecki.

528B. In vivo imaging of diacylglycerol signaling in a taste receptor neuron involved in salt-concentration memory. H. Ohno, Y. Iino.

529C. Genetic analysis of natural variations for cold habituation in C. elegans. M. Okahata, A. Ohta, Y. Minakuchi, A. Toyoda, A. Kuhara.

530A. Serotonin regulates dynamic feeding mode switching inducing predatory kinetics in Pristionchus pacificus. Misako Okumura, James W. Lightfoot, Martin Wilecki, Ralf J. Sommer.

531B. Cyclic GMP: A Satiety Signal in C. elegans. Ji Su Park, Young-Jai You.

532C. Pristionchus pacificus as a potential nematode model of aggression. Kathleen Quach, Shw Lew, Jagan Srinivasan, Matt Jones, James Fitzpatrick, Sreekanth Chalasani.

533A. The role of neuromodulators in regulating small molecule mediated mate recognition behavior. Douglas Reilly, Laura Aurilio, Florentia Ong, Jagan Srinivasan.

534B. TOR signaling pathway is involved in regulation of salt chemotaxis learning. Naoko Sakai, Masahiro Tomioka, Hayao Ohno, Hirofumi Kunitomo, Yuichi Iino.

535C. Dopamine Modulation of Electrotactic Swimming Behavior in C. elegans. Sangeena Salam, P. Ravi Selvaganapathy, Ram K. Mishra, Bhagwati P. Gupta.

536A. Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms. Stanislav Nagy, Nora Tramm, Jarred Sanders, Shachar Iwanir, Ian Shirley, Erel Levine, David Biron.

537B. A gustatory neural circuit for experience-dependent salt chemotaxis in C. elegans. Hirofumi Sato, Hirofumi Kunitomo, Xianfeng Fei, Koichi Hashimoto, Yuichi Iino.

538C. A scalable and cost-effective method for measuring pharyngeal pumping under controlled conditions. Monika Scholz, Kyung Suk Lee, Erel Levine, David Biron.

539A. The ENaC/degenerin Protein MEC-10 Regulates the Channel’s Response to Mechanical Forces. Shujie Shi, Thomas R. Kleyman.

540B. Study of transcriptome regulating a dispersal behavior in C. elegans. Sangwon Son, Harksun Lee, Junho Lee.

541C. Disruption of proteostasis induces sleep following heat shock. Rony Soto, Richard Mansfield, Andrew Hill, Adrig Sarian, Cheryl Van Buskirk.

542A. Assessment of DAF-19-Related Behavioral Defects. Loraina Stinson, Brian P. Piasecki, Debora Sugiaman-Trapman, Peter Swoboda.

543B. Systematic revere genetics approach to identify the molecules related to choice of behaviors using Caenorhabditis elegans.. Yuji Suehiro, Shohei Mitani.

544C. Modulation of glutamatergic signaling in C. elegans. Philip Summers, Amanda Ortega, Bruce Bamber, Richard Komuniecki.

545A. Eigenworm dynamics time series analysis reveals a lack of discrete behavioural states in C.elegans. Balazs Szigeti, Barbara Webb.

546B. Screening mutants defective in the forgetting of the olfactory adaptation of the odorants sensed by AWC neurons. Reo Takemoto, Tomohiro Kitazono, Akitoshi Inoue, Taksesi Ishihara.

547C. Distinct mechanisms underlie two types of Caenorhabditis elegans sleep. Nicholas Trojanowski, Matthew Nelson, Steven Flavell, Christopher Fang-Yen, David Raizen.

548A. INX-4/Innexin in AFD sensory neurons is required to regulate thermotaxis behavior in C. elegans. S. Tsukamoto, T. Emmei, N. Nishio, H. Sasakura, M. Akasaka, I. Mori.

549B. Ca2+ dependent negative feedback loop in AWC olfactory neurons: from mathematical viewpoint. Mamoru Usuyama, Sayuri Kuge, Takayuki Teramoto, Takeshi Ishihara, Yuishi Iwasaki.

550C. Contribution of protein localization to variability in salt chemotaxis behavior. Servaas van der Burght, Gert Jansen.

551A. Studying genetic control of yolk protein synthesis in relation to overall reproduction in C. elegans. Liesbeth Van Rompay, Charline Borghgraef, Jelle Caers, Isabel Beets, Liesbet Temmerman, Liliane Schoofs.

552B. Burrowing behavior of C. elegans used to study neuromuscular disorder models. Andres Vidal-Gadea, Celia Beron, Jesse Cohn, Adhishri Parikh, Grace Hwang, Jonathan Pierce-Shimomura.

553C. Investigating the neuromolecular mechanism for magneto-transduction in C. elegans. Chance Bainbridge, Trevor Rickert, Moe Khalil, Kristi Ward, Celia Beron, Navid Ghoashian, Sertan Gokce, Ophelia Papoulas, Daniel Boutz, Edward Marcotte, Adela Ben-Yakar, Andres Vidal-Gadea, Jonathan Pierce-Shimomura.

554A. Identification of nematodes volatile sex pheromone and the molecular basis of sex pheromone perception. Xuan Wan, King L. Chow.

555B. Investigating how glucose metabolism regulates neuromuscular circuit excitability in C. elegans males. Yufeng Wan, L. Rene Garcia.

556C. A Neural Circuit of Caenorhabditis elegans for Memory-Dependent Na+ Chemotaxis. L. Wang, M. Tomioka, H. Kunitomo, Y. Iino.

557A. TGFß mediates the feeding state-dependent expression of the food chemoreceptor ODR-10 in males. Emily R. Wexler, Deborah A. Ryan, Douglas S. Portman.

558B. Long-term imaging of circadian locomotor rhythms in C. elegans induced by temperature cycles. Ari Winbush, Matthew Gruner, Grant Hennig, Alexander van der linden.

559C. Elucidating the role of cGMP dynamics in behavioral plasticity. Sarah Woldemariam, Michelle Krzyzanowski, Mary Bethke, Martin Schneider, Jatin Nagpal, Alexander Gottschalk, Denise Ferkey, Noelle L'Etoile.

560A. Characterization of a sensory integration and associative learning gene. Glenn Wolfe, Vivian Tong, Derek van der Kooy.

561B. G-protein β subunit mediated signaling defines steady state serotonin biosynthesis in C. elegans chemosensory neurons. Lu Xu, Sunju Choi, Yusu Xie, Jiying Sze.

562C. Identifying neural signaling that cooperates with dopamine signaling in repulsive odor learning. Shuhei Yamazaki, Akiko Yamazoe, Kotaro Kimura.

563A. The effects of two neuropeptide receptors on general arousal level in C. elegans. Alex Yu, Evan Ardiel, Catharine Rankin.

564B. Adaptation in an axenic nutritional environment. Liusuo Zhang, L. Rene Garcia.

Neurobiology - Neuronal Development

565C. A tensin3 homolog SVH-6 regulates axon regeneration by stabilization of a MET-like receptor tyrosine kinase SVH-2. Tanimul Alam, Kazuma Asai, Naoki Hisamoto, Kunihiro Matsumoto.

566A. SLO K+ channels couple gap junctions to inhibit Ca2+ signaling in olfactory neuron diversification. Amel Alqadah, Hsieh Yi-Wen, Schumacher Jennifer A., Wang Xiaohong, Millington Grethel, Bayne Brittany, Chuang Chiou-Fen.

567B. Investigating the genetic basis of neuronal dimorphisms in C. elegans. Emily Bayer, Meital Oren-Suissa, Oliver Hobert.

568C. Finding Mutations that suppress the ciliary Degeneration Defect of ccpp-1 mutants in Caenorhabditis elegans. Sebastian Bellotti, Margaret Morash, Robert O'Hagan.

569A. A novel role for AEX-3, a guanine nucleotide exchange factor (GEF) for the Rab3 GTPase, in axon guidance. Jaffar M. Bhat, Harald Hutter.

570B. Heparan sulfate proteoglycans regulate cell migrations and organ polarity during development. Cassandra Blanchette, Andrea Thackeray, Paola Perrat, Siegfried Hekimi, Claire Bénard.

571C. sax-7 functions with nema-1 to maintain the architecture of the nervous system. Cassandra Blanchette, Andrea Thackeray, Claire Bénard.

572A. A 3D Analysis of the Mind of the Worm Connectome. Christopher Brittin, Steven Cook, Netta Cohen, David Hall, Scott Emmons.

573B. UNC-62 alternative transcripts differentially regulate UNC-55 expression and neural differentiation of GABAergic VD motor neurons. Richard Campbell, Walter W. Walthall.

574C. Novel regulators of the C. elegans UNC-6/Netrin pathway. Ranjan Devkota, Jason Chien, Gian Garriga, Catarina MÖrck.

575A. Role of DYF-7 in IL2 cell-body maintenance during dauer formation. K. M. Flatt, N. E. Schroeder.

576B. Cellular and Molecular Mechanisms Underlying Neurite Termination and Refinement in C. elegans. Maria Gallegos, Monika Avina, Lorrayne Serra, Boshika Tara, Joshua Azevedo, Catherine Ndungu-Case, Alejandro Flores, Pranti Das.

577C. Development of Caenorhabditis elegans GABAergic neurons. Marie Gendrel, Emily Atlas, Oliver Hobert.

578A. UNC-6/Netrin Repulsive Axon Guidance Involves UNC-33/CRMP and Flavin Monooxygenases. Mahekta Gujar, Erik Lundquist.

579B. Distinct microtubule organizations in ciliated and non-ciliated C. elegans neurons. Martin Harterink, Bart de Haan, Kah Wai Yau, Lucas Kapitein, Sander van den Heuvel, Casper Hoogenraad.

580C. Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. A. Alqadah, Y.-W. Hsieh, B. Vidal, C. Chang, O. Hobert, C.-F. Chuang.

581A. A negative relationship between pxn-1 and pxn-2 during neuronal development and aging in C. elegans. Gyujin Hwang, Jeong Hoon Cho.

582B. A Role for Peroxidasin PXN-1 in Aspects of C. elegans Development. Gyujin Hwang, Jeong Hoon Cho.

583C. Elucidating the Nervous System Role of UBC-1, an E2 Ubiquitin- Conjugating Enzyme in C. elegans. Qi Jin, Maria Lim, Jyothsna Chitturi, Mei Zhen.

584A. Hypergravity induces axon outgrowth defects in GABAergic motor neurons. Saraswathi Kalichamy, Tong Young Lee, Jin Il Lee.

585B. The ENU-3 protein family works in a pathway parallel to UNC-6/Netrin to promote motor neuron axon outgrowth in C. elegans and localize to the ER and nuclear membrane or are plasma membrane associated when expressed in HeLa cells. Marie Killeen, Roxana Florica, Victoria Hipolito, Homa Anvari, Chloe Rapp, Suzan ElRass, Mohammed Asgherian, Costin Antonescu.

586C. The evolutionary conserved LIM homeodomain protein LIM-4/LHX6 specifies the terminal identity of a cholinergic C. elegans sensory/inter/motor neuron-type. Jinmahn Kim, Jihye Yeon, Seong-Kyoon Choi, Yang Hoon Huh, Chris Li, Kyuhyung Kim.

587A. Genetic screens for IL2 lineage-specific regulators in Caenorhabditis elegans. Sungjong Kim, Soungyub Ahn, Dongjun Park, Peter Swoboda, Junho Lee.

588B. Using optical and molecular approaches to understand M4 neuronal defects in ceh-28 mutants. Alena Kozlova, Kalpana Ramakrishnan, Peter Okkema.

589C. The EAT-2 and GAR-3 acetylcholine receptors have distinct effects on pharyngeal muscle peristalsis. Alena Kozlova, Michelle Lotfi, Peter Okkema.

590A. The COE-type terminal selector UNC-3 cooperates with HOX proteins to generate motor neuron diversity. P. Kratsios, S. Y. Kerk, R. Mourao, O. Hobert.

591B. KIN-20 stabilizes neuronal architecture. . Matt LaBella, Kristin Moore, Edward Hujber, Randi Rawson, Nels Jorgensen, Michael Ailion, Julie Hollien, Erik Jorgensen.

592C. Redundant modular control of pan-neuronal gene expression in C. elegans. Nikolaos Stefanakis, Inés Carrera, Eduardo Leyva-Díaz, Oliver Hobert.

593A. C. elegans serotonergic neuron subtypes are regulated by different combinations of transcription factors. C. Lloret, M. Maicas, A. Jimeno, L. Chirivella, P. Weinberg, O. Hobert, N. Flames.

594B. Completing the de novo synthesis pathway for the coenzyme tetrahydrobiopterin (BH4) in C. elegans by structural modeling and mutant screening. Joachim Lätzer, Alec Knapp, Aleks Vitomirov, Curtis Loer.

595C. Identifying molecular drivers of neurogenesis. Neda Masoudi, Oliver Hobert.

596A. The degenerin/epithelial sodium channel protein UNC-8 drives activity-dependent synaptic remodeling in GABAergic neurons. Tyne W. Miller-Fleming, Sarah C. Petersen, Laura Manning, Cristina Matthewman, Megan Gornet, Sayaka Hori, Shohei Mitani, Laura Bianchi, Janet E. Richmond, David M. Miller III.

597B. Identification of the pathways by which post-translational microtubule glutamylation regulates ciliary maintenance in C. elegans. Robert O'Hagan, Maggie Morash, Sebastian Bellotti, Winnie Zhange, Maureen Barr.

598C. Towards the living connectome: generation of a 4D atlas of neurodevelopment. Mark Moyle, Anthony Santella, Ryan Christensen, Natasha Gutierrez, Ismar Kovacevic, Abhishek Kumar, Javier Marquina, Pavak Shah, Yicong Wu, Zhirong Bao, William Mohler, Hari Shroff, Daniel Colon-Ramos.

599A. Activation of Target Gene Expression in Neurons by the RFX Transcription Factor DAF-19. Katherine Mueller, Prasad Phirke, Debora Sugiaman-Trapman, Peter Swoboda, Elizabeth A. De Stasio.

600B. Genes Needed for Neuronal Ensheathment. eMalick Njie, Daniel Cabrera, Brian Cobiltz, Xiaoyin Chen, Martin Chalfie.

601C. The microRNA family mir-251/252 controls axonal guidance events in Caenorhabditis elegans. Steffen Nřrgaard, Roger Pocock.

602A. The EGF-like transmembrane protein c-tomoregulin acts in the UNC-6/Netrin pathway to mediate dendrite self-avoidance . Barbara O'Brien, Timothy O'Brien, Cody Smith, Sayaka Hori, Shohei Mitani, David Miller.

603B. gt1981 protects dopaminergic neurons from 6-OHDA-induced stress and ham-1 has a role in their specification. Sarah-Lena Offenburger, Dalila Bensaddek, Angus I. Lamond, Ralf Schnabel, Anton Gartner.

604C. Repression and Activation of Target Gene Expression in Polymodal Neurons by the RFX Transcription Factor DAF-19. Haili Olson, Prasad Phirke, Peter Swoboda, Elizabeth A. De Stasio.

605A. How does the KPC-1/Furin protease regulate dendrite arborization? Nelson Ramirez, Yehuda Salzberg, Julius Fredens, Nils Fćrgeman, Hannes Bülow.

606B. Genes involved in embryonic motor neuron positioning along the AP axis. Aysha C. Rankin, Matthew Tanner, Claire Robinson, Cristina Slatculescu, Theodore Perkins, Antonio Colavita.

607C. FKH-8, a winged-helix transcription factor, modulates dopamine neuron function. Corey Roach, Brian Nelms.

608A. WormGUIDES: The Making of the Worm’s Nervous System. Anthony Santella, Yicong Wu, Ismar Kovacevic, Abhishek Kumar, Javier Marquina-Solis, Raúl Catena, Ryan Christensen, Mark Moyle, Daniel Colón-Ramos, Hari Shroff, William A. Mohler, Zhirong Bao.

609B. Additional dimensions of glutamatergic neurotransmitter identity in the nervous system of C.elegans. Esther Serrano Saiz, Meital Oren, Oliver Hobert.

610C. NCX-9 regulates calcium exchange at the mitochondrion and is required for neural circuit patterning in Caenorhabditis elegans. V. Sharma, I. Seckler, D. O'Halloran.

611A. Genetic Screens Reveal Genes Regulating Ventral Nerve Cord Asymmetry in C. elegans. Jesse Taylor, Thomas Unsoeld, Harald Hutter.

612B. The transcription factor pros-1 is expressed in glia and regulates the morphology and function of sensory neurons. Sean Wallace, Yun Lu, Shai Shaham.

613C. Glial igdb-2 promotes amphid channel morphogenesis.. Wendy Wang, Elliot Perens, Shai Shaham.

614A. Investigation of the molecular mechanisms that mediate neural circuit formation. Aruna Varshney, Katherine Watters, Raakhee Shankar, Miri VanHoven.

615B. Transcriptional regulation and cis-regulatory logic of axon guidance cue receptors. Peter Weinberg, Oliver Hobert.

616C. Regionalization of male-specific ventral cord neurons by Hox neighbors LIN-39 and MAB-5. Andrea K. Kalis, Maria C. Sterrett, John G. D. Cannon, Georgia Schmitt, Shraddha Raghavan, Jennifer Ross Wolff.

617A. Developmental specification of a polymodal nociceptor in C. elegans. Jordan Wood, Denise Ferkey.

618B. A forward genetic screen identifies a modifier of a voltage- and calcium-activated K+ channel in left-right neuronal asymmetry. Rui Xiong, Xiaohong Wang, Chiou-Fen Chuang.

619C. The mir-234 microRNA promotes axon guidance by regulating UNC-6 independent UNC-40 signaling. Yan Xu, Christopher Quinn.

620A. The role of Hox genes in promoting both neuronal cell fate convergence and subtype diversification along the A-P axis. Chaogu Zheng, Felix Jin, Margarete Cuadros, Martin Chalfie.

Neurobiology - Novel Neuronal Methods

621B. Using retinal analogs and microbial rhodopsins as genetically encoded voltage sensors. N. AzimiHashemi, JF. Liewald, E. Rauch, M. Sheves, L. Kattner, A. Gottschalk.

622C. Si elegans - A neuromimetic emulation platform for exploring C. elegans’ neurobiology and behavior. Axel Blau, Frank Callaly, Gorka Epelde, Lorenzo Ferrara, Finn Krewer, Peter Leskovsky, Pedro Machado, Brian Mc Ginley, Martin McGinnity, Fearghal Morgan, Andoni Mujika, Alexey Petrushin, (The members of the Si elegans consortium are listed in alphabetical order).

623A. Understanding Neurodynamics Through Light Field Microscopy. Christopher Carmona, Edward Polanco, Blake Madruga, Addam Hammond, Katsushi Arisaka.

624B. Untwisting the Caenorhabditis elegans embryo. Ryan Christensen, Alexandra Bokinsky, Anthony Santella, Yicong Wu, Javier Marquina, Ismar Kovacevic, Abhishek Kumar, Peter Winter, Evan McCreedy, William Mohler, Daniel Colón-Ramos, Zhirong Bao, Hari Shroff.

625C. Directional trans-synaptic labeling of specific neuronal connections in live animals. Muriel Desbois, Steven J. Cook, Scott W. Emmons, Hannes E. Bülow.

626A. A Chemical-Genetic Approach to Unveil Mechanisms Underlying Autism Spectrum Disorders. Yasmin Fard Ghassemi, Kathrin Schmeisser, Claudia Maios, J. Alex Parker.

627B. A quenching-type of fluorescent Ca2+ indicator for detecting neuronal inhibition. Sayuri Kuge, Tomonobu Nishihara, Tomoki Matsuda, Hironobu Furuie, Takayuki Teramoto, Takeharu Nagai, Takeshi Ishihara.

628C. A Novel Worm Tracking Calcium Imaging System Utilizing a Mobile Microscope. Steve Mendoza, Tim Sherry, Karen Jiang, Brian Lam, Taejoon Kim, Blake Madruga, Michelle Kao, Nate Nowak, Katsushi Arisaka.

629A. Optogenetic control of cGMP mediated signal transduction . Jatin Nagpal, Shiqiang Gao, Martin Schneider, Mary Bethke, Chantal Brueggemann, Sarah Woldemariam, Wagner Steuer Costa, Noelle L'Etoile, Georg Nagel, Alexander Gottschalk.

630B. Drug screening in C. elegans leads to a clinical trial for amyotrophic lateral sclerosis. D. Aggad, K. Patten, G. Armstrong, C. Maios, L. Korngut, R. Robitaille, P. Drapeau, JA. Parker.

631C. Cell-Specific Labeling of Neurons and Glia in the C. elegans embryo using Infrared Laser Illumination. Anupriya Singhal, Shai Shaham.

632A. Computer simulation of neuronal signals controlling the pharyngeal pumping motion in Caenorhabditis elegans. Y. Hattori, M. Suzuki, T. Tsuji, Y. Kobayashi.

633B. Optophysiological dissection of individual dopaminergic neuron pairs during food-dependent behavioral modulation. Ying Grace Zheng, Yuki Tanimoto, Xianfeng Fei, Koichi Hashimoto, Kotaro Kimura.

634C. Neuronal mechanisms for C. elegans olfactory navigation revealed by a highly integrated microscope system. Yuki Tanimoto, Akiko Yamazoe, Kosuke Fujita, Yuya Kawazoe, Yosuke Miyanishi, Shuhei Yamazaki, Keiko Gengyo-Ando, Junichi Nakai, Xianfeng Fei, Yuishi Iwasaki, Koichi Hashimoto, Kotaro Kimura.

635A. Engineering the GAL4-UAS System for Transcriptional Control in C. elegans. Han Wang, Jonathan Liu, Shahla Gharib, John DeModena, Paul Sternberg.

636B. Automated Neural Identification in C. elegans. Eviatar Yemini, Oliver Hobert.

637C. Finding Neuro: Automating calcium image analysis. Amelia Parmidge, Chantal Brueggemann, Noelle L'Etoile, Jared Young.

Neurobiology - Regeneration and Degeneration

638A. DAPK-1: A Mediator of Excitotoxic Neurodegeneration. Uzair Amjad, Chantal Henry, Christy Chon, John S. Del Rosario, Itzhak Mano.

639B. Decreased SOD-1 function in a precise C. elegans ALS model leads to defective synaptic transmission and stress-induced neurodegeneration. Saba Baskoylu, Jill Yersak, Patrick O’Hern, Jonah Simon, Anne Hart.

640C. Molecular requirements of axonal regeneration in diapause . Mauricio Caneo, Mark Alkema, Andrea Calixto.

641A. The LIN-14 transcription factor regulates axonal maintenance in C. elegans neurons. Rhianna Knable, Justin Chaplin, Rhiannon Gurnsansky, Marie Gallegos, Brent Neumann, Massimo Hilliard.

642B. The role of a novel genetic factor (SLC30A10) in manganese-induced toxicity in C. elegans. Pan Chen, Dinorah Leyva-Illades, Aaron Bowman, Somshuvra Mukhopadhyay, Michael Aschner.

643C. Cyclic AMP and an Ets transcription factor are required for the transcriptional induction of svh-2 by axon severing. Li Chun, Hisamoto Naoki, Matsumoto Kunihiro.

644A. Delaying aging is neuroprotective in C. elegans models of Parkinson’s disease. Jason Cooper, Dylan Dues, Katie Spielbauer, Emily Machiela, Megan Senchuk, Jeremy Van Raamsdonk.

645B. C. elegans model of PGRN-deficient FTLD. James-Julian Doyle, Andrew Bateman, Hugh Bennett, Alex Parker.

646C. Is mitochondrial dysfunction a prerequisite for aging-related neurodegeneration? Using the PVD neuron as a model to study dendrite degeneration. Lezi E., Dong Yan.

647A. Repression of Neuronal Gene Expression by the RFX Transcription Factor, DAF-19. Zabdiel Ek-Vazquez, Savannah Vogel, Alex Hurlburt, Debora Sugiaman-Trapman, Peter Swoboda, Elizabeth A. De Stasio.

648B. The role of CRTC-1 in Abeta induced transcriptional dysregulation. Caroline Escoubas, William Mair.

649C. Mechanism of CREB Activation in Excitotoxicity-Induced Neuroprotection. K. Genevieve Feldmann, Itzhak Mano.

650A. Diet affects neurodegenerative processes in C. elegans. A. Fuentes, V. Garcia, MF. Palominos, A. Calixto.

651B. Activity dependent modulation of neuronal regeneration. Lin Sun, James Shay, Sam Chung, Christopher Gabel.

652C. AFF-1 fuses terminal branches non cell-autonomously during dendritic regeneration. Tamar Gattegno, Meital Oren-Suissa, Veronika Kravtsov, Benjamin Podbilewicz.

653A. Modulation of Transthyretin Degradation Alters Proteotoxicity in Caenorhabditis elegans Models of Degenerative Disease. Erin Greiner, Diana Porras-Gonzalez, Joseph Genereux, Johan Paulsson, Andrew Dillin, Jeffery Kelly, Sandra Encalada.

654B. Insulin Modulates the Outcome of alpha Synuclein Aggregation via Daf-2/Daf-16 Signaling Pathway by Acting as Antagonist for DAF-2 Receptor in Transgenic C. elegans Model of Parkinson’s Disease. Rizwanul Haque, Lalit Kumar, Shamsuzzama Shamsuzzama, Soobiya Fatima, Pooja Jadiya, Aamir Nazir.

655C. Age-related deterioration of neurons in male C. elegans. Michael Hart, Oliver Hobert.

656A. Statins in management of Neurodegenerative Parkinson’s disease: Studies employing Transgenic C.elegans Model.. Supinder Kaur, Aamir Nazir.

657B. A forward genetic screen for adult-onset motor deficits in C. elegans. K. Kawamura, T. Murayama, H. Goto, I. Maruyama.

658C. The role and regulation of a transcription factor, CEBP-1 in axon regeneration. Kyung Won Kim, Phoenix Ying, Thijs Koorman, Mike Boxem, Yishi Jin.

659A. Axon regeneration in mitochondrial mutants. Wendy Knowlton, Thomas Hubert, Andrew Chisholm, Yishi Jin.

660B. Identification of Dopamine Signaling Pathway Components that Modify Tau Neurotoxicity in Tau Transgenic Caenorhabditis elegans. Rebecca Kow, Jeanna Wheeler, Brian Kraemer.

661C. Single copy mutant TDP-43 and FUS transgenics cause age-dependent paralysis and neurodegeneration in C. elegans. Audrey Labarre, Julie Veriepe, Claudia Maios, J. Alex Parker.

662A. Necrotic Cells Actively Attract Phagocytes through the Collaborative Action of Two Distinct PS-exposure Mechanisms. Zao Li, Victor Venegas, Yuji Nagaoka, Eri Morino, Prashant Raghavan, Anjon Audhya, Yoshinobu Nakanishi, Zheng Zhou.

663B. Role of TDP-1 in RNA metabolism and heterochromatin formation. Chris Link, Tassa Saldi, Patrick Gonzales, Vishantie Dostal, Christine Roberts.

664C. Studying EFF-1 fusogen localization during C. elegans axonal regeneration. Casey Linton, Rosina Giordano-Santini, Brent Neumann, Sean Coakley, Massimo Hilliard.

665A. Contribution of DEG/ENaC channels conductance versus Ca2+ permeability to neuronal death. Cristina Matthewman, Laura Bianchi.

666B. Alaskan blueberry and Sirtuin 1-mediated neuroprotection in a Caenorhabditis elegans model of Parkinson's disease. Malabika Maulik, Sally Kuhn, Barbara E. Taylor.

667C. Identification of neuroprotective molecules using a C. elegans model of Spinal Muscular Atrophy. N. Mazzarella, I. Gallotta, M. A. Hilliard, E. Di Schiavi.

668A. The identification and characterization of SKN-1-associated acetylation pathways involved in dopamine neurodegeneration in Parkinson’s disease models. Richard Nass, Jonathan Trinidad, Jing Shi, Karen Ren.

669B. The role of miRNAs at the C. elegans neuromuscular junction: relevance to SMA. Patrick O'Hern, Jonah Simon, Anne Hart.

670C. Molecular and cellular characterization of SKN-1 and the multidrug resistance protein MRP-7 that inhibits toxicant-associated dopaminergic neurodegeneration. Karen Ren, Jonathan Trinidad, Jing Shi, Martina Rudgalvyte, Garry Wong, Richard Nass.

671A. Neuroprotective role of C. elegans sir-2.3 knock-out in neuronal death. Rachele Sangaletti, Jeff Grant, David Della Morte, Laura Bianchi.

672B. A novel target protects against APP-induced age-related neurodegeneration . L. L. Scott, J. Sahn, S. V. Iyer, G. Zuniga, P. Satarasinghe, S. Mondal, S. Martin, A. Ben-Yakar, J. Pierce-Shimomura.

673C. Identification of MOAG-2/LIR-3 as a regulator of protein aggregation. Olga Sin, Tristan de Jong, Michelle Kudron, Hai Hui Wang, Roméo Willinge Prins, Renée Seinstra, Alejandro Mata Cabana, Céline Martineau, Valerie Reinke, Victor Guryev, Ellen Nollen.

674A. Glia engulf AFD neuron receptive endings. Aakanksha Singhvi, Andrea Bae, Shai Shaham.

675B. Modelling Alzheimer’s disease: transgenic expression of human Aβ peptides in Caenorhabditis elegans neurons. Neha Sirwani, Kirsten Grant, Warwick Grant, Gawain McColl.

676C. Understanding the regulation of TDP-43 phosphorylation in a C.elegans model for diseases with TDP-43 positive lesions. Laura Taylor, Nicole Liachko, Aleen Saxton, Pam McMillan, Tim Strovas, Brian Kraemer.

677A. Drug screening for C9ORF72 toxicity. Martine Therrien, Simon Girard, Guy A. Rouleau, Patrick A. Dion, J. Alex Parker.

678B. Probing the Mechanisms by Which Exercise Enhances Axon Regrowth. Guoqiang Wang, Christopher Reina, Isaac Song, Monica Driscoll.

Neurobiology - Synaptic Function and Circuits

679C. The common neighbor rule as an organizing principle in the C. elegans neural network. Aharon Azulay, Eyal Itskovic, Alon Zaslaver.

680A. Neuropeptide signaling sets the timing of C. elegans egg-laying.. Navonil Banerjee, Raja Bhattacharya, Michael M. Francis.

681B. Molecular and Behavioral Studies of Sexually Dimorphic Electrical Synaptic Connectivity. Emily Berghoff, Abhishek Bhattacharya, Meital Oren-Suissa, Oliver Hobert.

682C. The atypical MAP kinase SWIP-13 exerts cell-autonomous control of dopamine signaling and behavior. Daniel P. Bermingham, J. Andrew Hardaway, Sam L. Snider, Sean P. Moran, Sarah M. Sturgeon, Randy D. Blakely.

683A. Competing activation and inhibition in the Caenorhabditis elegans egg-laying behavior circuit. Kevin Collins, Addys Bode, Robert Fernandez, Jessica Tanis, Matt Creamer, Michael Koelle.

684B. Elucidating the role of the novel transcription factor FKH-8 in regulating dopaminergic signaling levels.. Kai Bracey, Brian Nelms.

685C. The HSN command neuron co-releases serotonin and NLP-3 neuropeptides to coordinate egg-laying activity. Jacob Brewer, Michael R. Koelle.

686A. Spatial aggregation of neurons contributes to network structure in the nematode C. elegans. Christopher Brittin, Steven Cook, Netta Cohen.

687B. Determining the role of the transcription factor FKH-8 in C. elegans dopamine-dependent behaviors. Ke'Ara Brown-Smith, Dr. Brian Nelms.

688C. Molecules involved in the biogenesis of dense-core vesicles. Jerome Cattin, Irini Topalidou, Michael Ailion.

689A. Investigating the Potential Role of the Transcription factor FKH-8 in Dopamine Metabolism. Bryan Cawthon, Brian Nelms.

690B. Spatio-temporal regulation of RAB-3 localization and activity by SNT-1. Yunsheng Cheng, Jiaming Wang, Yu Wang, Mei Ding.

691C. A two-immunoglobulin-domain transmembrane protein mediates an epidermal-neuronal interaction to maintain synapse density. Salvatore Cherra, Yishi Jin.

692A. INX-1 is a Negative Regulator of the Expulsion Step of the Defecation Motor Program. Ukjin Choi, Han Wang, Derek Sieburth.

693B. The UNC-7 gap junction mediates a D2-like signaling pathway in a sensory motor recurrent circuit during C. elegans copulation. Paola Correa, Luis Rene Garcia.

694C. The appetite control circuit in C. elegans. Kristen Davis, Young-Jai You.

695A. Modulation of habituation and neurotransmitter vesicle release by a D2-like dopamine auto-receptor. Rosaria Formisano, Mahlet Mersha, Courtney McClure, Sailaja Mandalapu, Harbinder S. Dhillon.

696B. Molecular and cellular mechanisms regulating axonal compartmentalization in C. elegans RIA interneurons. A. Donato, J. Ren, Y. Zhang, M. A. Hilliard.

697C. G-Protein Coupled Receptor Signaling: a Role for Small Interfering RNAs in Stimulus Specific Adaptation. Trang Duong, Noelle L'Etoile.

698A. Whole-animal C. elegans connectomes. S. Emmons, S. Cook, T. Jarrell, Y. Wang, M. Yakovlev, K. Nguyen, D. Hall.

699B. Defining interactions between neurotransmitter transporters and proton pumps. G. Ernstrom, D. Jenkins, L. Folger.

700C. A functional screen for homologs of the dopamine-gated chloride channel LGC-53. Alice Fok, Niels Ringstad.

701A. Elucidating conserved neural mechanisms underlying defective motor pattern transitions. Dawn Guzman, Jonathan Pierce-Shimomura.

702B. Long-term associative memory in Caenorhabditis elegans. Satomi Ito, Saori Nishigima, Ichiro Maruyama.

703C. Testable hypothesis generation via directed analysis of plausible information flow in the connectome. Rex Kerr.

704A. A gene expression-analysis approach to identify the genetic code for synaptic connections in the C. elegans nervous system. Byunghyuk Kim, Bangxia Suo, Maria Lazaro-Pena, Olha Ivashkiv, Scott W, Emmons.

705B. An atlas of G protein-coupled neurotransmitter and neuropeptide receptor expression patterns in C. elegans. Seongseop Kim, Robert Fernandez, Judy Pepper, Michael R. Koelle.

706C. The G protein-coupled receptor FSHR-1 regulates the balance of excitatory to inhibitory transmission at the C. elegans neuromuscular junction. Allyson Munneke, Sarah Olofsson, Amy Wasilk, Julie Kolnik, Erica Damler, Jennifer Kowalski.

707A. Cold habituation is regulated by the tissue network including neuron and sperm. Satoru Sonoda, Tomoyo Ujisawa, Akane Ohta, Atsushi Kuhara.

708B. Calcium imaging and computational simulation for the spatio-temporal dynamics of the neural coding in a C. elegans chemotaxis circuit. Masahiro Kuramochi, Motomichi Doi.

709C. Adaptation to cholinergic agonist levamisole, a new insight of AChR regulation at neuromuscular junctions. Viviane Laine, Luis Briseno-Roa, Maelle Jospin, Jean-Louis Bessereau.

710A. Functional and anatomical analysis of the L1 motor circuit. Sway Chen, Steven Cook, Asuka Guan, Yangning Lu, Valeriya Laskova, Jeff Lichtman, Ben Mulcahy, James Mitchell, Marianna Neubauer, Aravinthan Samuel, Manusnan Suriyalaksh, Richard Schalek, Quan Wen, Daniel Witvliet, Mei Zhen.

711B. Line scanning fluorescent confocal microscope for a 3D multi-neuron imaging of C. elegans. Alexey Lyashenko, Edward Polanco, Katsushi Arisaka.

712C. Investigating the synaptic role of the Gαs pathway. Laura Manning, Ashley Martin, Om Bhetuwal, Janet Richmond.

713A. Regulation of the nicotinic acetylcholine receptor ACR-16. Ashley Martin, Feyza Sancar, Janet Richmond.

714B. Understanding motor circuit regulation through genetic suppressor analyses of acr-2(gf) . Katherine McCulloch, Yishi Jin.

715C. Locating synaptic calcium channels. Sean Merrill, Shigeki Watanabe, Alex Cherry, Erik Jorgensen.

716A. UNC-16 (JIP3) acts through synapse assembly proteins to inhibit the active transport of cell soma organelles to motor neuron axons. Stacey Edwards, Logan Morrison, Rosalina Yorks, Christopher Hoover, Soorajnath Boominathan, Kenneth Miller.

717B. An INX-16 mediated calcium wave is required for normal NLP-40 release. Samuel McCright, Gabriel Moore, Christopher Ayoub, Lisa Learman, Maureen Peters.

718C. Genetic analysis of a synapse to nucleus feedback mechanism coupling synaptic glutamate receptor levels with transcription. Benjamin Moss, Peter Juo.

719A. The mind of an L1 worm – how do neuronal circuits function and remodel throughout development?. Daniel Berger, Andrew Chisholm, Steven Cook, Scott Emmons, David Hall, Douglas Holmyard, David Kersen, Valeriya Laskova, Jeff Lichtman, James Mitchell, Ben Mulcahy, Marianna Neubauer, Angie Qu, Aravinthan Samuel, Richard Schalek, Daniel Witvliet, Mei Zhen, (names in alphabetical order).

720B. Electrophysiological properties of ASE neurons. Tomomi Shindou, Mayumi Shindou, Takashi Murayama, Jeffery Wickens, Ichiro Maruyama.

721C. Thermal memory and behavioral regulation revealed by calcium imaging of the cultured neurons and neural circuits. Kyogo Kobayashi, Shunji Nakano, Mutsuki Amano, Daisuke Tsuboi, Tomoki Nishioka, Shingo Ikeda, Genta Yokoyama, Kozo Kaibuchi, Ikue Mori.

722A. Identifying and characterizing odor receptors in C. elegans. Sara Nathan, Alesha Cox-Harris, Cassidy Dalton, Berenice Mosqueda, Sherrlyne Apostol, Riva Morton, Elizabeth Newman, Chantal Brueggemann, Noelle L'Etoile, Jared Young.

723B. Distinct pharyngeal glutamate determinants underpinning the context dependent modulation of feeding behaviour. Vincent O'Connor, Nicolas Dalliere, Bhatla Nikhil, Horvitz Robert, Holden-Dye Lindy, Walker Robert.

724C. CREB facilitates a replacement of temperature experience-linked cold tolerance. Akane Ohta, Makoto Ioroi, Natsune Takagaki, Atsushi Kuhara.

725A. The Role of Post-Translational Modifications in the Regulation of Serotonin Signaling. Andrew C. Olson, Michael R. Koelle.

726B. Investigation of spine-like synaptic structures on GABAergic DD neurons. Alison Philbrook, Steven J. Cook, David H. Hall, Michael M. Francis.

727C. An Investigation into the Affect of Neuronal Activity on Proper Neural Connectivity in C. elegans. Kristine Andersen*, Benjamin Barsi-Rhyne*, Jacqueline Pyle, Kristine Miller, Christopher Vargas, Aruna Varshney, Bryan Tsujimoto, Alan Tran, Alex Duong, Joori Park, Emma Holdrich, Miri VanHoven.

728A. Development of activity in the Caenorhabditis elegans egg-laying circuit. Bhavya Ravi, Kevin Collins.

729B. Exposure to Nicotine or the Putative GABA agonist Toluene Differentially Modulates Expression of GABA Signaling Elements and Alters Mobility in C. elegans. . Jacqueline Rose, Parker Stafford, Nicole Stankowicz, Amanda Leonti.

730C. C. elegans touch neurons express plasma membrane innexin channels. Rachele Sangaletti, Gerhard Dahl, Laura Bianchi.

731A. Rab G-protein regulation of Neurexin localization in C. elegans neurons. Sanil Sansar, Komla Segagbe, DiAnna Hynds, Tina Gumienny.

732B. Glial cues and neuronal cGMP together regulate sensory neuron receptive ending shape and function. Aakanksha Singhvi, Shai Shaham.

733C. Identifying neuronal dynamics of short-term associative memory in C. elegans. A. Sylvain, M. Rahimi, G. Stein, C. T. Murphy.

734A. Plasticity of cold habituation and isolation of genes involved in temperature experience storage. Natsune Takagaki, Tomohiro Ishiwari, Yohei Minakuchi, Atsushi Toyoda, Akane Ohta, Aysushi Kuhara.

735B. A novel mutation in the ligand-gated ion channel lgc-46 affects excitation-inhibition imbalance in the C. elegans locomotor circuit. Seika Takayanagi-Kiya, Salvatore Cherra, Yingchuan B. Qi, Yishi Jin.

736C. A forward genetic screen for regulators of neuronal two-pore domain potassium channel. Philippe Tardy, Mélissa Zouak, Thomas Boulin.

737A. Cloning and characterization of three new players in the Gαq and Rho signaling pathways. Jill Hoyt, Irini Topalidou, Brantley Coleman, Michael Ailion.

738B. GLB-33: when a globin hooks up with a G-protein coupled receptor. M. Vangheel, S. De Henau, L. Tilleman, F. Germani, I. Beets, S. Helbo, F. Desmet, H. Berghmans, S. Van Doorslaer, D. Hoogewijs, L. Schoofs, A. Fago, L. Moens, S. Dewilde, B. P. Braeckman.

739C. NLP-12 Engages Different UNC-13 Proteins to Potentiate Tonic and Evoked Release. Zhitao Hu, Amy Vashlishan Murray, Joshua Kaplan.

740A. Serotonin-mediated second messengers act in distal metabolic tissues to regulate fat in C. elegans. Megan Vaughan, Lavinia Palamiuc, Tallie Noble, Supriya Srinivasan.

741B. Elucidating the role of interneuron RIM in the regulation of C. elegans locomotion. Khursheed A. Wani, Zhaoyu Li, Beverly J. Piggott, Shawn Xu.

742C. Circuit underpinnings for integrated behavioral responses to multiple sensory cues. W. Yang, Y. Zhang.

743A. AFD-specific guanylate cyclases and CMK-1 mediate thermosensory signaling in AFD. Yanxun Yu*, Asuka Takeishi*, Vera Hapiak, Harrold Bell, Piali Sengupta.

744B. Menorah Analyzer – a MATLAB based software for the analysis of 2D images of the PVD neuron in C.elegans. Omer Yuval, Tamar Gattegno, Benjamin Podbilewicz, Tom Shemesh.

Ecology and Evolution - Ecology

745C. The C. elegans gut microbiota and its significance to its host. Maureen Berg, Ben Stenuit, Joshua Ho, Caitlin Parke, Lisa Alvarez-Cohen, Michael Shapira.

746A. Intermittent stem cell cycling balances self-renewal and senescence of the C. elegans germ line. Amanda Cinquin, Michael Chiang, Adrian Paz, Sam Hallman, Oliver Yuan, Charless Fowlkes, Olivier Cinquin.

747B. Relating life history to population dynamics: a perspective on aging. A. Earnest, S. K. Kornfeld.

748C. Widespread maternal effects shape the Caenorhabditis elegans life history. Helen Orbidans, Alice Moorey, James Green, Simon Harvey.

749A. Natural Variation in Pathogen-induced Neuronal Gene Expression in C. elegans. Zoe Hilbert, Joshua Meisel, Dennis Kim.

750B. ­Is nematode host preference associated with the beetle bacterial microbiome? A case study in Los Angeles. Sneha Koneru, Michael Gonzalez, Heilly Salinas, Gilberto Flores, Ray Hong.

751C. A simple 3D cultivation system to measure C. elegans fitness in a semi-natural simulated environment. Tong Young Lee, Jin Il Lee.

752A. Survey of the genetic structure of a C. elegans wild population at a local scale by 2b-RAD-sequencing. Aurélien Richaud, Marie-Anne Félix.

753B. Natural microbial engagement of small RNA pathways in C. elegans. Buck Samuel, Holli Rowedder, Gary Ruvkun.

754C. Construction of Ecologically Relevant Microcosms for the Quantification of Changes in Population Size of C. elegans. Kevin G. Sanchez, Brian P. Mikeworth, Lisa N. Petrella.

755A. The natural microbiota of C. elegans.. Hinrich Schulenburg, Philipp Dirksen.

Ecology and Evolution - Evo-Devo

756B. The propensity for stochastic PCD during male tail development varies across C. elegans isotypes. Melissa Alcorn, Davon Callander, Bilge Birsoy, Matthew Cieslak, Agustín López Santos, Joel Rothman.

757C. Cubist biology — using evolutionary perspectives to define regulatory pathways. Yongquan Shen, Qing Wei, Yanmnei Zhao, Shin-Yi Lin, Xiangmei Chen, Ronald Ellis.

758A. Implications of transcription factor binding site turnover in orthologous cis-regulatory regions. Lori Glenwinkel, Oliver Hobert.

759B. Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer. Tamar Hashimshony, Martin Feder, Michal Levin, Brian Hall, Itai Yanai.

760C. Pharyngeal gland development in the root-knot nematode Meloidogyne hapla. R. A. Loewen, V. W. Williamson, M. Tenuta, J. Kormish.

761A. Evidence for a C. briggsae X-linked hybrid lethal gene that encodes a transcription factor. Vaishnavi Ragavapuram, Scott Baird.

762B. Changing the shape of a tupe in the evolution of organogenesis. David Rudel, Kelly Mahoney, Brent Wyatt, Blake Rumble, Sharon Arhin.

763C. Unusual sex determination systems in Bursaphelenchus okinawaensis and B. xylophilus. Ryoji Shinya, Taisei Kikuchi, Isheng J. Tsai, Anthony Chen, Koichi Hasegawa, Paul W. Sternberg.

764A. Extreme variation in the requirement for SKN-1 in endoderm development reflects both genomic variation and stably heritable epigenetic states that differ between isotypes. Yamila Torres Cleuren, Kyle Chipman, Coco Alami, Russell Snell, Joel Rothman.

Ecology and Evolution - Evolution of Complex Traits

765B. Mechanism of peel-1 toxicity. Elyse Blum, Jerome Cattin, Michael Ailion.

766C. An experimental evolution model of C. Elegans adaptability. Bradly Alicea, Rebecca Androwski, Nathan Schroeder.

767A. Preparing Panagrellus redivivus for molecular genetics. David Angeles Albores, Daehan Lee, Junho Lee, Paul Sternberg.

768B. Mutation is a sufficient predictor of genetic variation for mitotic spindle traits in C. elegans. Reza Farhadifar, Charles Baer, Jose Miguel Ponciano, Erik Andersen, Daniel Needleman.

769C. Evolutionary variation in heat-triggered multigenerational onset of sterility in C. elegans. Lise Frézal, Eric Miska, Marie-Anne Félix.

770A. Natural variation and developmental plasticity of hitchhiking behavior in C. elegans. Daehan Lee, Harksun Lee, Boyun Lee, Jun Kim, Heeseung Yang, Heekyeong Kim, Young-ki Paik, Leonid Kruglyak, Erik Andersen, Junho Lee.

771B. Rictor limits temperature-dependent dauer formation by controlling intestine-neuron signaling. Mike O'Donnell, Jan Kammenga, Piali Sengupta.

772C. Rapid accumulation of variation in mutation rate under relaxed selection in C. elegans. Ayush Shekhar Saxena, Matthew Salomon, Matsuba Chikako, Baer Charles.

773A. Acute stress resistance, DR and Lifespan in a multi-parent recombinant inbred line panel. Jana Stastna, L. Basten Snoek, Rita Volkers, Joost Riksen, Alex Vujakovic, Hinrich Schulenburg, Jan Kammenga, Simon Harvey.

774B. A powerful C. elegans resource for identifying the genetic determinants underlying complex traits. S. Zdraljevic, S. Rosenberg, R. E. Tanny, T. S. Shimko, E. C. Andersen.

775C. A C. elegans large-scale genome-wide association study reveals hundreds of quantitative trait loci underlying responses to biomedically relevant therapeutics. S. Zdraljevic, S. Rosenberg, R. E. Tanny, T. C. Shimko, E. C. Andersen.

Ecology and Evolution - Evolution of Mating Systems

776A. PQN-94 Regulates Hermaphrodite Development by Interacting with SHE-1. Yongquan Shen, Ronald Ellis.

777B. Complex regulation of the GLI transcription factor tra-1 in C. briggsae.. Yongquan Shen, Emmalisa Zapfe, Yelena Shifman, Ronald Ellis.

778C. Genome sequence of a parthenogen closely related to Caenorhabditis reveals fusion of all ancestral chromosomes. H. Fradin, C. M. Zegar, M. R. Gutwein, J. Lucas, M. Kovtun, D. L. Corcoran, L. R. Baugh, K. Kiontke, K. Gunsalus, D. H. A. Fitch, F. Piano.

779A. CNP-2, a calcineurin interacting protein, regulates male development, mating behavior, and sperm activation. Hana Jung, Joohong Ahnn, Sun-Kyung Lee.

780B. Evolution of hermaphroditism in Caenorhabiditis species. Katharine Pelletier, Keith Reidy, Dave Pilgrim.

781C. Maternal specification of dauer formation and sex determination in a species with three sexes. Andre Pires da Silva, Sophie Tandonnet.

782A. Sex-ratio bias in Caenorhabditis. Yun-Hua Lo, Jung-Chen Hsu, Fang-Jung Yang, Tiffany Chang, Son Tho Le, John Wang.

783B. Characterizing the structural basis and functional consequences of genome shrinkage in selfing Caenorhabditis species. Da Yin, Erich Schwarz, Caitlin Schartner, Edward Ralston, Barbara Meyer, Eric Haag.

Ecology and Evolution - Phylogeny and Diversification

784C. Genome wide analysis of adaptation to acidic environments of the extremophile Turbatrix aceti. Amit Sinha, Jennifer Pirri, Peter Sarkies, Mark Alkema.

785A. The Caenorhabditis Genomes Project. Mark Blaxter, Lewis Stevens, Sinduja Chandrasekar, Georgios Koutsovoulos.

786B. Genetics and development in speciation of Caenorhabditis. Asher Cutter, Joanna Bundus.

787C. A new evolutionary framework for the phylum Nematoda: a case study of HOX cluster evolution. G. Koutsovoulos, D. R. Laetsch, T. Breeze, M. L. Blaxter.

788A. Hybrid Incompatibility in Caenorhabditis nouraguensis. Piero Lamelza, Janet Young, Harmit Malik, Michael Ailion.

789B. Notable characteristics of Caenorhabditis sp. 34, a novel species associated with figs. Gavin Woodruff, Taisei Kikuchi, Natsumi Kanzaki.

Development - Cell Fate and Patterning

790C. Microfluidic C. elegans immobilization, enabling long-term studies of germline development at a single-cell resolution. Simon Berger, Xavier Casadevall i. Solvas, Stavros Stavrakis, Tinri Aegerter-Wilmsen, Ralf Eberhard, Alex Hajnal, Michael Hengartner, Andrew deMello.

791A. Towards an understanding of how embryos cope with stochastic gene expression. Hailey Choi, Gina Broitman-Maduro, Francisco Carranza, Kollan Doan, Morris Maduro.

792B. The Paired-Box protein PAX-3 is involved in hypodermal cell fate specification in C. elegans. Kenneth W. Thompson, Margarita Correa-Mendez, Christine Y. Kang, David M. Eisenmann.

793C. Functional analysis of the C. elegans winged-helix transcription factor LIN-31 identifies multiple domains and separation-of-function mutations in vulval cell fate specification. Amanda Dewey, Leilani Miller.

794A. Elucidating the role of nmy-2 in seam cell division patterns. Siyu Serena Ding, Alison Woollard.

795B. Transcriptional control of the C. elegans endoderm master regulator elt-2. Lawrence Du, Sharon Tracy, Allison Wu, Scott Rifkin.

796C. Lipid asymmetry and signaling regulation during vulva development. Juan Escobar Restrepo, Andrea Haag, Alex Hajnal.

797A. Sequential Muscle Cell Fate Determination by Overlapping Functions of Different Transcription Factors in the Descendants of the Anterior Mesoderm Blastomere (MS). Tetsunari Fukushige, Rossio Kersey, Micheal Krause.

798B. pal-1 regulates polarized apical junction remodeling and cell movement during the development of the C. elegans epidermis. Sophie P. R. Gilbert, Charles Brabin, Alison Woollard.

799C. LEP-2/Mkrn promotes degradation of LIN-28 to time the larval-to-adult transition. R. A. Herrera, K. Kiontke, D. Fitch.

800A. MicroRNA pathways and developmental elasticity in C. elegans. O. Ilbay, J. Srinivasan, F. Schroeder, V. Ambros.

801B. MAB-5/Hox non-autonomously controls Q descendant migration through regulation of spon-1/F-spondin expression in posterior body wall muscles. Matthew Josephson, Adam Miltner, Erik Lundquist.

802C. Quantitative Analysis of the AC/VU Decision during C. elegans Development. Simone Kienle, Nicola Gritti, Yvonne Goos, Jeroen van Zon.

803A. Mechanism and significance of the maternal mex-3 mRNA localization in C. elegans. Hiroyuki Konno, Koki Noguchi, Yuji Kohara.

804B. Transcriptional Regulation of the Hox Gene LIN-39 by LIN-1 and LIN-31 Transcription Factors Involved in C. Elegans Cell Fate Specification. Robert Kousnetsov, Kyle Tamshen, Amanda Dewey, Leilani Miller.

805C. The identification of SYS-1/β-catenin binding partners and transactivation domains in the Wnt/β-catenin asymmetric pathway. Arielle Lam, Amy Clemons, Michael Molumby, Lori Adams, Bryan Phillips.

806A. The CRL2LRR-1 ubiquitin ligase regulates Notch signaling in C. elegans vulva development. Madhumati Mukherjee, Edward T. Kipreos.

807B. Temporal constraints and regulation of embryonic gene expression. John Murray, Travis Walton.

808C. MEX-5 interacts with the mRNA transcription and degradation machineries. Costanza Panbianco, Manoel Prouteau, Monica Gotta.

809A. Differential APR-1 regulatory role for two Dishevelled paralogs during asymmetric cell division. Bryan Phillips, Austin Baldwin.

810B. usp-48 encodes a ubiquitin-specific protease involved in cell fate restriction. Dylan Rahe, Oliver Hobert.

811C. Analysis of Phosphorylation of the C. elegans Transcription Factor LIN-31 During Cell Signaling. Hayley Raquer, Amanda Dewey, Leilani Miller.

812A. Putative RAP-1 function in a positive feedback loop to reinforce Ras/LET-60-dependent 1° VPC commitment. N. Rasmussen, D. Reiner.

813B. Identification of genes involved in Sex Muscle patterning in C. elegans hermaphrodite. S. Sammons, K. Sun, H. Shi, V. Ghai, S. Son, J. Liu.

814C. The small GTPase Ral signals via an Exo84-GCK-2/MAP4K-p38-MAPKAPK cascade to induce 2° vulval fate.. Hanna Shin, Rebecca E. W. Kaplan, Channing J. Der, David J. Reiner.

815A. Using Genetic Screens to Initiate Undergraduate Research: Identifying Regulatory Cofactors of the Caenorhabditis elegans Cellular Fusogen, EFF-1, and Their Effects on Epithelial Cell Fusion. Patrick Spica, Emra Klempic, Matthew Betzenhauser, William Mohler, Jessica Shinn-Thomas.

816B. LIN-14 transcriptionally regulates lin-4 and let-7 family miRNAs, which in turn negatively regulate LIN-28. Jennifer Tsialikas, Mitchell Romens, Allison Abbott, Eric Moss.

817C. Canalization of C. elegans vulva induction against anatomical variability. Guizela Huelsz-Prince, Jeroen van Zon.

818A. How are unilateral neurons specified? The role of Notch. Berta Vidal Iglesias, Oliver Hobert.

819B. Searching for missing interactions that link vulval cell differentiation and vulval morphogenesis using logical modeling of regulatory networks. Nathan Weinstein, Luis Mendoza.

820C. The FAX-1 and NHR-67 nuclear receptors function in gonad development. Bruce Wightman, Emily Bayer, Leen Jerjos, Christopher Greco, Mackenzie Kramer`, Michael Kho, Katie Skwirut, Akshara Kartik, Sheila Clever.

Development - Differentiation and Plasticity

821A. Uncovering Molecular Barriers to Direct Cell Reprogramming in C. elegans. Oktay Ismail Kaplan, Idris Selman Bulut, Baris Tursun.

822B. P granules maintain germ cell identity in the C. elegans germline. Andrew Knutson, Thea Egelhofer, Andreas Rechtsteiner, Lynnia Tuckfield, Susan Strome.

823C. Increasing histone H3K9 methylation and nucleosome stability promote higher-order nuclear re-organization during embryogenesis. Beste Mutlu, Huei-Mei Chen, Jie Wang, David Hall, Tao Liu, Susan Mango.

824A. Food-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling. Scott Neal, Asuka Takeishi, Rebecca Butcher, Kyuhyung Kim, Piali Sengupta.

825B. A high-throughput EMS screen identifies a potential muscle linage mutant. Andreas Ofenbauer, Ralf Schnabel, Baris Tursun.

826C. Asymmetric Wnt Pathway Regulation of Post-embryonic Seam Cell Proliferation and Identity via the Non-receptor Tyrosine Kinase FRK-1. Adriana Calderon, Danielle Mila, McLane Watson, Katherine Genzink, Austin Baldwin, Bryan Phillips, Aaron Putzke.

827A. The TFIIH and SWI/SNF complexes are required for the cell fate maintenance in C. elegans. Yukimasa Shibata, Ryoji Konakawa, Hitoshi Sawa, Kiyoji Nishiwaki.

828B. TRIMming pluripotency. C. Tocchini, J. J. Keusch, S. B. Miller, S. Finger, H. Gut, M. B. Stadler, R. Ciosk.

Development - Germline Development and Sex Determination

829C. Quantitative and spatial changes in GLD-1 accumulation distinguish direct gld-1 regulators from non-regulators. John Brenner, Tim Schedl.

830A. CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline. Anne Campbell, Dustin Updike.

831B. Regulation of C. elegans Sperm Motility By Protease Signaling. Daniela Chavez, Gillian Stanfield.

832C. Ras/ERK pathway and retinoblastoma associated protein RbAp46 regulate synaptonemal complex dynamics during prophase I of meiosis. Jie Chen, Shin-Yu Chen, Swathi Arur.

833A. Overlapping and Distinct Effects of Bisphenol A and its Substitute Bisphenol S on Germ Cells. Y. Chen, D. Lee, P. Allard, X. Yang, L. Shu.

834B. Accelerating the quest for fertilization: Premature sperm activation induced by mutations in Y48B6A.5 and spe-47. Jessica Clark, Craig LaMunyon.

835C. Sexually dimorphic GSCs and development of tools to manipulate them. Sarah L. Crittenden, Anne R. Ryan, Brandon Taylor, Ipsita Mohanty, ChangHwan Lee, Judith Kimble.

836A. Identification of novel genes regulating P-granule function in C. elegans. Karolina de Groot-Andralojc, Markus Terrey, Michael Senter-Zapata, Benjamin King, Anne Campbell, Dustin Updike.

837B. How to remain inactive: maintaining the spermatid stage requires inhibition and properly formed FB-MOs. Aubrie De La Cruz, Matthew Christensen, Haifen Huang, Thomas Sokolich, Gaurav Prajapati, Jessica Clark, Nicholas Sullivan, Craig LaMunyon.

838C. LAF-1 is an intrinsically disordered P granule component that contributes to asymmetric phase separation during C. elegans embryogenesis. Krzysztof Szczepaniak, Shana Elbaum-Garfinkle, Younghoon Kim, Carlos Chih-Hsiung Chen, Sua Myong, Clifford Brangwynne, Christian Eckmann.

839A. The zinc transporter HKE-4.1 controls sperm activation. Yanmei Zhao, Chieh-Hsiang Tan, Kerry Kornfeld, Ronald Ellis.

840B. SNF-10, a Solute Carrier 6 family protein, connects male-derived protease signals to the onset of sperm motility. Kristin Fenker, Gillian Stanfield.

841C. MEL-28 and dynein/dynactin components interact to affect fertility. Jesse Conklin, Angela Quental, Allison Lai, Fabio Piano, Anita Fernandez.

842A. Germline defects in mitochondrial cholesterol transporter C. elegans mutants following bisphenol A or low cholesterol exposures. D. W. Ferreira, P. Allard.

843B. Investigating mechanisms that promote and limit meiotic CO formation. Chloe Girard, Baptiste Roelens, Karl Zawadzki, Anne Villeneuve.

844C. Role of proteoglycans in germline development . Sandeep Gopal, Roger Pocock.

845A. Role of the Anillin ANI-2 in the nucleation of the C. elegans germline syncytium. Eugénie Goupil, Jean-Claude Labbé.

846B. MRG-1 and RFP-1 regulate proliferation in the germline. P. Gupta, L. Leahul, C. Wang, X. Wang, D. Hansen.

847C. Regulation of RNP granule remodeling in the germ line. Dustin Haskell, Megan Karrick, Megan Wood, Jennifer Schisa.

848A. LST-1 and SYGL-1, key regulators of germline stem cell fate . Kimberly A. Haupt, Heaji Shin, Aaron M. Kershner, Judith Kimble.

849B. A computational model of cell mechanics and decision-making in the C. elegans germ line. K. Atwell, Z. Qin, H. Kugler, D. J. Gavaghan, E. J. A. Hubbard, J. M. Osborne.

850C. Role of Glycogen Synthase Kinase 3 beta in C. elegans germline development. Hyoe-Jin Joo, Shin-Yu Chen, Tokiko Furuta, Jessica Jie Chen, Kenneth Trimmer, Swathi Arur.

851A. The putative helicase ddx-15 plays a role in ribosome biogenesis and germline development. Jonathan Karpel.

852B. Monitoring S-phase in aging wild type and mutant C. elegans germlines using EdU labeling and a GFP:PCNA transgene. Zuzana Kocsisova, Ariz Mohammad, Tim Schedl, Kerry Kornfeld.

853C. spe-43 is a member of the spe-8 class of genes and is required for spermiogenesis in C. elegans. Amber Krauchunas, Ernesto Mendez, Jean Parry, Andrew Singson.

854A. Investigating the function of HOP-1 presenilin in germ line development. Donna Leet, Brian Brady, Valerie Hale, Caroline Goutte.

855B. PUP-1 and PUP-2: two redundant poly(U) polymerases regulating C. elegans germline development. Yini Li, Matt Snyder, Eleanor Maine.

856C. Analysis of a new genetic enhancer of glp-1. Jim Lissemore, Francisco Gomez-Chaves, Joshua Krach, Chelsea Pallo, Jill Spoerke, Eleanor Maine.

857A. A genetic screen for mutants with defects in the regulation of gonad membrane dynamics during adult oogenesis. Josh Lowry, Bruce Bowerman.

858B. Visualization of regulated transcription using single-molecule FISH. Tina R. Lynch, ChangHwan Lee, Judith Kimble.

859C. PUF-8 promotes niche-germline stem cell signalling via the ER protein FARL-11. Richa Maheshwari, Pushpa Kumari, Kuppuswamy Subramaniam.

860A. Primordial germ cell survival requires niche cell conact in the C. elegans gonadal primordium. Daniel McIntyre, Jeremy Nance.

861B. The Dynamics of Alternative Polyadenylation Usage in C. elegans Germ Cell Development. Desirea G. Mecenas, Sean M. West, Michelle Gutwein, Wenting Bian, Jerome Reboul, Jola Polanowska, Kristin C. Gunsalus, Fabio Piano.

862C. LIN-35 is Necessary for Germ Line Development and Function When Faced With High Temperature Stress. Brian P. Mikeworth, Lisa N. Petrella.

863A. SCF complex and GLD-1 function together to repress germ cell proliferation but are not needed for initiation of meiotic gene expression. Ariz Mohd, Tim Schedl.

864B. Splicing machinery potentiates post-transcriptional regulation of germline development. Preston Novak, Xiaobo Wang, Mary Ellenbecker, Sara Feilzer, Ekaterina Voronina.

865C. CDK-11.1 regulates signalling between sperm and egg during fertilization. Christopher Williams, Kevin O'Connell.

866A. The Role of Histone H3 Lysine 9 Trimethylation in Germ Cell Development. J. Olson, E. Voronina.

867B. Development and sex ratio distortion of the cockroach-gut parasitic nematodes. S. Ozawa, R. Sriwati, R. Shinya, T. Kikuchi, K. Hasegawa.

868C. A Novel Pathway for Germ Cell Differentiation in C. elegans. Mainpal Rana, Jeremy Nance, Judith Yanowitz.

869A. Preferential misregulation of spermatogenesis genes in male sterile C. nigoni carrying an X-linked C. briggsae fragment. Yu Bi, Xiaoliang Ren, Cheung Yan, Jiaofang Shao, Runsheng Li, Dongying Xie, Zhongying Zhao.

870B. A search for lst-1 and sygl-1 enhancers. Sarah L. Robinson, Aaron M. Kershner, Heaji Shin, Kimberly A. Haupt, Peggy Kroll-Conner, Judith Kimble.

871C. Understanding the cell cycle dynamics of germline stem/progenitor cells during expansion and maintenance phases. Debasmita Roy, David Michaelson, Anthony Santella, Tsivia Hochman, Judith Goldberg, Zhirong Bao, E. Jane Albert Hubbard.

872A. Re-visiting the cell-cycle length of mitotic germ cells. Hannah Seidel, Judith Kimble.

873B. Nutritional control of adult germ cell divisions in C. elegans. Hannah Seidel, Judith Kimble.

874C. Studies on the function of heparan sulfate in C. elegans germline development. D. C. Severiano da Cunha, K. Ames, H. Nader, A. Meléndez, H. Bülow.

875A. Identification of regulators of sperm motility in C. elegans males. Tyler Shimko, Daniela Chavez, Gillian Stanfield.

876B. CUP-2, a Derlin protein, promotes Notch signalling in C. elegans. Ramya Singh, Xin Wang, Tiffany Sutton, Kevin Kowalchuk, Hilary Racher, Dave Hansen.

877C. A genetic screen for fertilization mutants identifies an Izumo-like gene. Gunasekaran Singaravelu, Sina Rahimi, Amber Krauchunas, Anam Rizvi, Sunny Dharia, Diane Shakes, Harold Smith, Andy Golden, Andrew Singson.

878A. The Elusive role of APH-2 in the C. elegans gonad. Karen Smith, Cassandra Farnow, Caroline Goutte.

879B. ChIP-Seq analysis of GLP-1/Notch signaling target genes in germline stem cells. Erika B. Sorensen, Elena P. Sorokin, Amy C. Groth, Judith Kimble.

880C. Cloning the male sterile, sperm defective genes fer-2 and fer-3. D. Starr.

881A. The highly divergent germ line in Strongyloididae. Arpita Kulkarni, Anja Holz, Dorothee Harbecke, Christian Roedelsperger, James W. Lightfoot, Adrian Streit.

882B. PUF-8 and TOCA-2 regulate mitochondrial dynamics to control germline apoptosis. A. Chaturbedi, M. Ariz, K. Subramaniam.

883C. spe-45 is essentially required during gamete fusion like mouse Izumo1. T. Tajima, J. Takayama, S. Onami, S. W. L'Hernault, H. Nishimura.

884A. A sperm-derived ion channel TRP-3 induces a Ca2+ wave in the fertilized C. elegans oocyte. J. Takayama, S. Onami.

885B. hke-4.1/ ZIP7 encodes a zinc transporter involved in zinc homeostasis and sperm function in Caenorhabditis elegans. Chieh-Hsiang Tan, Yanmei Zhao, Nicholas Dietrich, Kurt Warnhoff, Ronald E. Ellis, Kerry Kornfeld.

886C. Lineage Tracing in the C. elegans Germline. K. Trimmer, S. Arur.

887A. Membrane Remodeling in the C. elegans Germ Line. Alicia Trombley, Megan Wood, Michael Davis, Kevin Schmidt, Jennifer Schisa.

888B. A role for dynein light chain in germline stem cell maintenance in C. elegans. Xiaobo Wang, Mary Ellenbecker, Dominique Rasoloson, Ekaterina Voronina.

889C. Fam20C function in C. elegans. Carolyn Worby, Adena Gerson-Gurwitz, Karen Oegema, Arshad Desai, Jack Dixon.

890A. Omega-6 polyunsaturated fatty acid is required for yolk endocytosis and lipid uptake in C. elegans oocytes examined by CARS microscopy. Yung-Hsiang Yi, Wei-Wen Chen, Tian-Hsiang Ma, Kuei-Ching Hsiung, Kuan-Yu Liu, Cheng-Hao Chien, Yi-Chun Lin, Yu-Sun Chang, Szecheng J. Lo, Ta-Chau Chang.

Development - Morphogenesis

891B. exc-2, a gene involved in maintaining tube structure of the excretory canals. Hikmat Al-Hashimi, Matthew Buechner.

892C. The DevoWorm Project: raising the worm with data. Bradly Alicea, Stephen Larson, Steven McGrew, Richard Gordon.

893A. Charcterising the role of ZK185.1 in Caenorhabditis elegans embryonic contraction. Elizabeth D. Drewnik, Ben G. Chan, Ryan B. Smit, Paul E. Mains.

894B. Critical roles for the apical extracellular matrix in C. elegans excretory duct and pore tube development. Hasreet Gill, Jennifer Cohen, Rachel Forman-Rubinsky, Pu Pu, Meera Sundaram.

895C. ­Decoding Embryonic Developmental Pathways Using 4D-High Content Imaging of C. elegans embryos. Rebecca Green, Stacy Ochoa, Renat Khaliullin, Zhiling Zhao, Shaohe Wang, Ronald Biggs, Adina Gerson-Gurwitz, Arshad Desai, Karen Oegema.

896A. Multiple DUF23 proteins are required for normal surface coat, bacterial biofilm formation, pathogen susceptibility and viability. Jonathan Hodgkin, Maria J. Gravato-Nobre, Dave Stroud, Delia O'Rourke.

897B. FBN-1 is an apical matrix protein essential for the integrity of epithelial organs under mechanical stress during larval development. S. Katz, H. Maul-Newby, T. Chong, V. Meli, A. Frand.

898C. Characterizing tension-dependent events required for post-embryonic development of the epidermis. Sophie Katz, Alison Frand.

899A. A novel regulatory network in C. elegans embryos contributes to epidermal structural integrity during development. Melissa Kelley, David Fay.

900B. Gene expression during C. elegans male sexual maturation. Byunghyuk Kim, Bangxia Suo, Scott W. Emmons.

901C. Blister formation in bli-5 is suppressed by knocking down nas-36 and nas-37. Sedona Murphy, Anna Malawista, Timothy Chaya, Philip Meneely.

902A. in vivo Mechanisms of Epithelial Cell Junction Formation. Jose Montoyo-Rosario, Jeremy Nance.

903B. Assessing the Pathogenicity of Orsay Virus Capsid Protein Using PROFECE. Frederic Pio, Ombeline Hueber, Michelle Mony, Alex Bikov.

904C. Nematode moulting enzymes as potential drug targets. Gillian Stepek, Gillian McCormack, Doug Houston, Malcolm Walkinshaw, Antony Page.

905A. C. elegans WD40 domain containing protein LAWD-1 possibly mediates protein-protein interactions during epithelial morphogenesis. Mengmeng Qiao, Patricia Kuwabara.

906B. Finding the GAPs Between the Membrane Receptors and CED-10/Rac1 During Embryonic Epidermal Morphogenesis . Hamidah Raduwan, Martha Soto.

907C. Genetic Analysis of the formin fhod-1 and the PP2c phosphatase fem-2 genes during C. elegans embryonic elongation. Osama Refai, Paul Mains.

908A. Dissecting the teratogenic effects of an insect host pheromone in Pristionchus pacificus embryos. Tess Renahan, Ray Hong.

909B. Nucleolar size scaling in multicellular growth and development. Sravanti Uppaluri, Stephanie Weber, Clifford Brangwynne.

910C. Neuroblasts mechanically influence epidermal morphogenesis. Denise Wernike, Karina Mastronardi, Yun Chen, Alisa Piekny.

911A. The role of a claudin superfamily gene nsy-4 in male sensory organ development of C. elegans. Dongying Xie, King L. Chow.

912B. Identification of DMD-3 targets in the C. elegans male tail tip. Ji-Sup Yang, R. Antonio Herrera, Karin Kiontke, Hana Littleford, Emily Williams, Adam Mason, Sevinc Ercan, David Fitch.

913C. Identifying a role of N-glycosylation in C. elegans epithelial polarity by an RNAi-based biosynthetic-pathway-screen approach. Hongjie Zhang, Nessy Abraham, Liakot Khan, Nan Zhang, Verena Gobel.

Development - Signaling Pathways in Development

914A. Examining interactions between AMPK and HIF-1 during C. elegans development in hypoxia. Stacy Alvares, Courtnee Clough, Dana Miller.

915B. RHO-1 is required for normal oocyte transit through the spermatheca. Alyssa D. Cecchetelli, Erin J. Cram.

916C. Wnt canonical and calcium pathways regulate cytoskeletal changes in the C. elegans male anal depressor . Xin Chen, Luis Rene Garcia.

917A. Wnt signaling regulates midline guidance in C. elegans. Jason Chien, Ranjan Devkota, Catarina Mörck.

918B. EKL-7 is a putative MPK-1 Erk target during excretory duct cell fate specification. Preston Chin, Phil Cheng, Christian Rocheleau.

919C. Functions of C. elegans lin-28 in hermaphrodite fertility. Sungwook Choi, Anna Zinovyeva, Victor Ambros.

920A. Coordinating Cdk1 and Plk1 activation for mitotic entry in early C. elegans embryos and human cells. L. Cirillo, Y. Thomas, C. Panbianco, L. Martino, F. Schwager, L. Van Hove, A. Santamaria, L. Pindard, M. Gotta.

921B. Identifying the cell-type origins of secreted VPR-1 MSP domains. T. Cole, J. Winek, J. Vibbert, P. Cottee, J. Chen, M. Miller.

922C. A role for insulin signaling in development of the parasitic nematode Brugia malayi. Kirsten Crossgrove, Danielle Zgoba, Lee Smith, Jenna Maiorelle.

923A. Computational model of EGF/Ras and Notch signaling in Caenorhabditis vulval development. Adriana Dawes, David Wu, Karley Mahalak, Edward Zitnik, Natalia Kravtsova, Haiwei Su, Helen Chamberlin.

924B. Dsh-1/Dishevelled attenuates the repelling activity of Wnt signaling in neurite outgrowth. Margarete Diaz-Cuadros, Chaogu Zheng, Martin Chalfie.

925C. The Rheb-TORC1 signaling axis and screening for Million Mutation Project alleles. Tam Duong, F. Sefakor Mote, David J. Reiner.

926A. The insulin pathway and its relation to diapause and starvation in beet cyst nematodes (Heterodera schachtii). Syed Jehangir Shah, Florian M. W. Grundler, Abdelnaser Elashry.

927B. Defining genetic pathways of disease through genetic suppression screens in Caenorhabditis elegans. Amy Fabritius, Andy Golden.

928C. Functional analysis of the LIN-2/7/10 complex in LET-23 EGFR localization and signalling during vulval development. Kimberley Gauthier, Olga Skorobogata, Christian Rocheleau.

929A. The Mediator CDK-8 Module Represses EGFR Signaling by Modulating LIN-1 Transcription Factor and Mediator Activity. Jennifer Grants, Lisa Ying, Akinori Yoda, David Matus, Charlotte You, Hideyuki Okano, Hitoshi Sawa, Stefan Taubert.

930B. Control of TGF-beta DBL-1 secretion in C. elegans. Kathy Beifuss, Robbie Schultz, Geethanjali Ravindranathan, Tina Gumienny.

931C. Complementary approaches to dissect C. elegans Notch receptor/ligand interactions. Laurie Holt, Bogusia Korona, Richard Suckling, Susan Lea, Alison Woollard, Penny Handford.

932A. dbl-1/TGF-β and daf-12/NHR signaling mediate cell-nonautonomous effects of daf-16/FOXO on starvation-induced developmental arrest. Rebecca Kaplan, Yutao Chen, James Jordan, Ryan Baugh.

933B. Two ubiquitin conjugating enzymes (E2s) coordinately regulate pharyngeal attachment in C. elegans. Hilary Kemp, Katja Dove, Rachel Klevit, Dana Miller.

934C. Adult Reproductive Diapause and Embryo Arrest in C. elegans. Isabel Kenny, Bree Heestand, Bergit Gerisch, Adam Antebi, Shawn Ahmed.

935A. Determining the mechanism of spindle positioning in response to the Src polarity cue. Malgorzata J. Liro, Lesilee S. Rose.

936B. Three conserved tetraspanin proteins promote bone morphogenetic protein (BMP) signaling . Zhiyu Liu, Lin Wang, Herong Shi, Jun Liu.

937C. Population density in Caenorhabditis elegans controls developmental rate via a small molecule-based push-pull strategy . A. H. Ludewig, C. Gimond, J. J. Judkins, R. M. Micikas, F. Doering, C. Braendle, F. C. Schroeder.

938A. moa-1 links the APP-related gene apl-1 to the heterochronic pathway. Vanessa Marfil, Swera Cheema, Chris Li.

939B. Identifying the proteolytic and functional pathways of APL-1, the C. elegans homolog to human APP. Alexander Mir, Alexander Chait, Chris Li.

940C. Genetic Circuitry of the Molting Cycle Timer. R. Mushtaqh Ali, A. R. Frand.

941A. The lipocalin LPR-1 cooperates with LIN-3/EGF signaling to promote excretory duct tube morphogenesis . P. Pu, M. Sundaram.

942B. An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signalling in the VPCs. Olga Skorobogata, Christian Rocheleau.

943C. The ZEN-4 Kinesin and DHC-1 Dynein microtubule motors promote and antagonize LET-23 EGFR signaling in the VPCs. Olga Skorobogata, Jassy Meng, Christian Rocheleau.

944A. Development of early C. elegans embryos in a temperature gradient provides evidence for a cell-non-autonomous coordination system. Eric Terry, Bilge Birsoy, Marin Sigurdson, Dave Bothman, Carl Meinhart, Joel Rothman.

945B. Mechanisms of SYS-1/β-catenin centrosomal localization in early embryonic blastomeres. Josh Thompson, Setu Vora, Bryan Phillips.

946C. Life and death: discerning the role of the essential gene, lim-7. Laura Vallier, Vidia Ramadin, Arnold Mahabir.

947A. Assessing the evolution of lin-3 and the activities of its splice forms in Caenorhabditis vulval development. Amhed Vargas Velazquez, Marie-Anne Felix.

948B. GRK-2 regulates body development through TGF-beta pathway in C. elegans. Jianjun Wang, Richard Carr, Jeffrey Benovic.

949C. Modifications in the EGF/Ras/MAPK signalling via hypoxia. Duygu Yucel.

950A. Analyses of the mmBCFA-TORC1 pathway controlling postembryonic development and foraging behavior. H. Zhu, M. Kniazeva, A. Sewell, K. Anderson, F. Jia, M. Han.

Gene Regulation and Genomics - Databases and Programs

951B. a platform to study alternative polyadenylation in C. elegans. S. M. Blazie, K. Kotagama, M. Mangone.

952C. Parasitic WormBase. Bruce Bolt, Michael Paulini, Paul Davis, Thomas Down, Jane Lomax, Gary Williams, Kevin Howe, The WormBase Consortium.

953A. JBrowse: A new genome browsing tool for WormBase. Scott Cain, Todd Harris, Sibyl Gao, Lincoln Stein.

954B. SeqPlots - a fast interactive web tool for visualizing next generation sequencing signals along genomic features. Przemyslaw Stempor, Julie Ahringer.

955C. The WormBase Community Curation Project. Mary-Ann Tuli, Juancarlos Chan, Ranjana Kishore, Daniela Raciti, Xiaodong Wang, Karen Yook, Paul Sternberg.

956A. WormBase Gene Curation using WebApollo. Gareth Williams, Bruce Bolt, Paul Davis, Thomas Down, Jane Lomax, Michael Paulini, Kevin Howe, The WormBase Consortium.

Gene Regulation and Genomics - Epigenetics

957B. Developing a system for cell-specific isolation of extrachromosomal transgene arrays. Kevin Adams, Colton Kempton, Steven Johnson.

958C. Remodeling X chromosome topology during dosage compensation. Erika Anderson, Qian Bian, Barbara J. Meyer.

959A. Chromatin modifiers in dosage compensation and cell cycle. Elizabeth Brouhard, Gyorgyi Csankovszki.

960B. Examining environmental effects on the germline epigenome. Jessica Camacho, Zachary Lundby, Linzi Hosohama, Amander Clark, Patrick Allard.

961C. Transcriptional regulation of metabolic genes by promoter-localized O-GlcNAc. Ainhoa Ceballos, Germano Cecere, Alla Grishok.

962A. AMX-1 and AMX-2, Amine Oxidase Domain Containing Proteins with Varied Activities. Reetobrata Basu, Janet Duerr.

963B. Competition between the long and short DOT-1.1 isoforms modulates H3K79 methylation and gene expression in the embryo. R. Esse, G. Cecere, A. Grishok.

964C. Integrating environmental cues during development: An epigenetic bookmark of hydrogen sulfide. Emily Fawcett, Jenna Johnson, Dana Miller.

965A. Loss of synMuv B proteins resuls in extended open chromatin environments during early development. Meghan E. Fealey, Lisa N. Petrella.

966B. Analysis of RNA editing regulation and function. Nabeel Ganem, Ayelet Lamm.

967C. Epigenetic Regulation and the O-GlcNAcase: OGA as a Nutrient Sensitive Eraser and Reader of the Histone Code. Katryn Harwood, John Hanover.

968A Unprogrammed presentation number

969B. Chromosome-scale and local patterns of nucleosome fragility in C. elegans. Tess Jeffers, Jason Lieb.

970C. Histone modifications are required for the persistence of hydrogen sulfide memory in C. elegans. Jenna Johnson, Emily Fawcett, Dana Miller.

971A. DNA sequence and its influence on gene expression and chromatin architecture. Colton Kempton, Collin Skousen, Julie Roberts, Katie Church, Daniel Evans, Steven M. Johnson.

972B. Epigenetic inheritance of ethanol preference in C. elegans. Kaeli Knudsen, Hillary Parker, Chris Todd, Jose Andres, Carlos Carvalho.

973C. Spatial organization of chromosomes in polyploid nuclei of C. elegans. Kristina Krassovsky, Barbara J. Meyer.

974A. Transgenerational response to a challenging environment in C. elegans. I. Lev, O. Rechavi.

975B. Study of transgenerational inheritance of acquired odor-related traits in Caenorhabditis elegans. Fernando Munoz-Lobato, Noelle D. L'Etoile.

976C. The Argonaute CSR-1 mediates genome-wide chromatin remodeling and gene expression changes resulting from distinct early life history events. M. Ow, S. Hall.

977A. Description of two synMuv B Suppressor Genes Identified from a Genome-Wide RNAi Screen. Nicholas B. Sepulveda, Lisa N. Petrella.

978B. Epigenetic landscape of C. elegans sperm chromatin. Tomoko Tabuchi, Andreas Rechtsteiner, Susan Strome.

979C. A laboratory adaptation in the nucleosome remodeling factor nurf-1 in C.elegans regulating epigenetic changes in the nervous system. W. Xu, P. T. McGrath.

980A. Identifying genes involved in H3K9me2 regulation in C. elegans. Bing Yang, Xia Xu, Eleanor Maine.

Gene Regulation and Genomics - Gene Regulation

981B. Investigating the regulation of temporal co-expression of cuticle collagen genes in C. elegans. P. Abete-Luzi, D. M. Eisenmann.

982C. Novel regulators of RUNX transcription factor in Caenorhabditis elegans. Soungyub Ahn, Hyun-Seok Oh, Peter Swoboda, Jongsik Chun, Junho Lee.

983A. Chromsosomal context influences X chromosome targeting by the C. elegans Dosage Compensation Complex. Sarah Albritton, Lara Winterkorn, Anna-Lena Kranz, Sevinc Ercan.

984B. Casein kinase 2 facilitates target binding and silencing of the microRNA Induced Silencing Complex in C. elegans. Amelia F. Alessi*, Vishal Khivansara*, Ting Han*, Mallory A. Freeberg, James J. Moresco, Patricia G. Tu, Eric Montoye, John R. Yates III, Xantha E. Karp, John K. Kim.

985C. The roles of CpG density and H3K4me3 at C. elegans promoters. Ron Chen, Przemyslaw Stempor, Yan Dong, Carolina Gemma, Jurgen Janes, Eva Zeiser, Sky Feuer, Thomas Down, Julie Ahringer.

986A. In vivo protein interaction mapping in C. elegans embryos. Jia-Xuan Chen, Patricia Cipriani, Desirea Mecenas, Jolanta Polanowska, Fabio Piano, Kristin Gunsalus, Matthias Selbach.

987B. Detection of promoter-terminator loops at active germline genes by 3C . Blanca Craven-Bartle, Alla Grishok.

988C. A novel role for LET-23 in lipid synthesis via the transcription factor SBP-1. Niko Contos, Matt Crook.

989A. A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. C. Cubillas, H. Roh, K. Kornfeld.

990B. Identification of an enhancer element that mediates transcriptional activation in response to low dietary zinc. Nicholas Dietrich, Kurt Warnhoff, Daniel Schneider, Hyun Roh, Kerry Kornfeld.

991C. Separating the different contributions of the GATA factors ELT-2 and ELT-7 to intestinal gene expression. A. Dineen, E. Osborne Nishimura, A. Robinson, J. Lieb, J. Rothman, J. McGhee.

992A. Specificity of binding site selection by the C. elegans dosage compensation complex. Anna-Lena Kranz, Sevinc Ercan.

993B. Mapping chromatin accessibility using ATAC-seq in C. elegans. Victoria Ettorre, Sevinc Ercan.

994C. The role of general transcription factors in dosage compensation. Nicholas Fuda, Barbara Meyer.

995A. Regulation of gene expression by the DREAM complex. C. Gal, M. Chesney, I. Latorre, A. Appert, J. Ahringer.

996B. Identifying components of the germ cell transcriptional regulatory network activated upon loss of the Dp, Rb, and MuvB (DRM) complex. Paul Goetsch, Susan Strome.

997C. Mediator Subunit cdk-8 and GATA Factor elt-2 Form a Pathway Regulating Cadmium-Inducible Gene Expression. Jennifer Grants, Anik Muhuri, Grace Goh, Stefan Taubert.

998A. Putative binding site for Odd-skipped transcription factors in the promoters of C. elegans germline genes. Garrett M. Dancik, Meaghan M. Kennedy, Alice A. DiFrancesco, Amy C. Groth.

999B. Weird gene structure: the 5’ region of mRNA for the essential glycosyltransferase BUS-8 encodes a cis-acting regulatory peptide. Delia O'Rourke, Dave Stroud, Jonathan Hodgkin.

1000C. blmp-1 positively regulates bed-3. Hei Tung Fong, Jin Yang, Zhengyang Xie, Jason Tan, Takao Inoue.

1001A. H4K20me1, a player in cell cycle and dosage compensation. Jianhao Jiang, Laura Custer, Györgyi Csankovszki.

1002B. Identification of novel Kallmann syndrome genes by fluorescence activated cell sorting and expression profiling. Samuel Keenan, Alyse Steves, Taylor Voyles, Joy Chibuzo, Alicia Schwieterman, Martin Hudson.

1003C. Developmental dynamics of X chromosome dosage compensation in C. elegans. M. Kramer, A.-L. Kranz, A. Su, L. Winterkorn, S. Albritton, S. Ercan.

1004A. RNA code and protein structure determining the specificity of mRNA regulation by the TRIM-NHL protein LIN-41. Pooja Kumari, Cristina Tocchini, Jeremy Keusch, Heinz Gut, Rafal Ciosk.

1005B. Exploring the relation between transcription factor binding affinity and target gene activation. Brett Lancaster, James McGhee.

1006C. Network analysis of time-resolved transcriptome data reveals interactions among genes and signaling pathways that affect the susceptibility of C. elegans to P. aeruginosa PA14 infection. Lucy Lee, Javier Irazoqui, Erel Levine.

1007A. Communication between daf-7/TGFβ and the insulin-like peptide network connects food abundance to longevity. Chang Liu, Eugeni V. Entchev, Dhaval S. Patel, Giovanni Diana, Mei Zhan, Hang Lu, QueeLim Ch'ng.

1008B. Tissue homogeneity requires embryonic inhibition of stochastic RNA silencing. Hai Le, Lanelle Edwards, Monika Looney, Benjamin Strauss, Michael Bloodgood, Antony Jose.

1009C. Effects of introns on gene expression. Alexander Mendenhall, Bryan Sands, Roger Brent.

1010A. Large scale RNAi screening for vitamin B12-related processes. Huimin Na, Albertha J. M. Walhout.

1011B. Cell-specific and sub-cellular mRNA patterning in early embryogenesis. Erin Osborne Nishimura, Sophie Tintori, Jay C. Zhang, Adam D. Wertz, Bob Goldstein, Jason D. Lieb.

1012C. The effects of Cyclosporin A on gene expression in Caenorhabditis elegans. David Pertab, Vicky Butler, Tony Page.

1013A. It’s expression o’clock: Understanding cell-intrinsic regulation of gene expression. Euclides F. Póvoa, Lorenzo Rella, Annabel L. P. Ebbing, Marco C. Betist, Hendrik C. Korswagen.

1014B. Evolutionary Comparison of Dosage Compensation Between C. elegans and C. briggsae. Emily Powers, Te-Wen Lo.

1015C. Comparative genomics of cholinergic gene locus structure and regulation. Jim Rand, Ellie Mathews, Greg Mullen.

1016A. Manganese-induced gene expression changes in Caenorhabditis elegans. Martina Rudgalvyte, Juhani Peltonen, Merja Lakso, Richard Nass, Garry Wong.

1017B. Enhancer Regulatory Logic Controlling the Muscle-Hypodermal Differentiation Decision in the Caenorhabditis elegans C Lineage. Jonathan Rumley, Amanda Zacharias, John Murray.

1018C. Mechanism of dosage compensation complex spreading . Mohammad Sadic, Sarah Albritton, Anna-Lena Kranz, Sevinc Ercan.

1019A. Transcriptional regulation in stress recovery of Caenorhabditis elegans . Mark G. Sterken, L. Basten Snoek, Roel P. J. Bevers, Joost A. G. Riksen, Jan E. Kammenga.

1020B. Insulation of Nuclear Receptor Gene Regulation by Boundary Effectors. Deborah Thurtle, Keith Yamamoto.

1021C. Evolution of the GATA family of transcription factors in nematodes. Christian Turner, Morris Maduro.

1022A. A Novel bacterial factor involved in the infection of Caenorhabditis elegans by Pseudomonas aeruginosa. Alejandro Vasquez-Rifo, Emiliano Ricci, Melissa Moore, Victor Ambros.

1023B. Microfluidic high-throughput fluorescence-based sorter for studying stochastic expression of heat shock proteins on C. elegans. Nadia Vertti-Quintero, Xavier Casadevall i. Solvas, Oliver Dressler, Stavros Stavrakis, Jan Gruber, Rudiyanto Gunawan, Andrew deMello.

1024C. Determining when, where, and how much each gene is expressed, and the regulatory relationships between them. Adam D. Warner, Timothy J. Durham, Chau Huynh, Robert H. Waterston.

1025A. Beyond Cell Death: Comprehensive Analyses of Non-apoptotic CED-3 Caspase Functions. Benjamin Weaver, Yi Weaver, Min Han.

1026B. ELT-2 can specify, differentiate and maintain the C. elegans intestine in the absence of the endoderm factors END-1,END-3, ELT-4 and ELT-7. Tobias Wiesenfahrt, Janette Berg, Erin Osborne Nishimura, Jason Lieb, James McGhee.

1027C. Deciphering the regulation of FLP-8 induction in dauer touch receptor neurons. Tian Xia, Roger Pocock.

1028A. A genetic E. coli screen to identify genes that regulate C. elegans size. Jingyan zhang, Albertha JM Walhout.

Gene Regulation and Genomics - Genomics

1029B. Genetic control of cell-specific susceptibility to protein aggregation. Jasmine Alexander, Mingjie Ying, Tali Gidalevitz.

1030C. Comparative Transcriptomic Analysis of Individual Embryos during Embryonic Development between Three Steinernema Species. Marissa Macchietto, Dristi Angdembey, Nicole El-Ali, Ali Mortazavi.

1031A. A model for feeding-site formation by root-knot nematode. David Bird.

1032B. An integrative analysis of alternative polyadenylation and miRNA regulation in C. elegans. S. Blazie, C. Babb, H. Wilky, A. Rawls, J. G. Park, M. Mangone.

1033C. An annotated genome of the root-knot nematode, Meloidogyne chitwoodi. S. Cha, D. Bird.

1034A. CGC ver 2.0: What you need to know. Aric Daul, Theresa Stiernagle, Julie Knott, Kemi Awoyinka, Ann E. Rougvie.

1035B. From genetic interaction modules to robustness and evolution of a multicellular organism. Benjamin Boucher, Anna Lee, Michael Hallett, Sarah Jenna.

1036C. A mechanistic study of alternative polyadenylation in C. elegans. K. Kotagama, S. M. Blazie, C. Babb, K. Ramirez, H. Wilky, M. Mangone.

1037A. Comparative genomics of Steinernema reveals deeply conserved regulatory networks in nematodes. Marissa Macchietto, Adler Dillman, Camille Porter, Alicia Rogers, Brian Williams, Igor Antoshechkin, Ming-Min Lee, Zane Goodwin, Xiaojun Lu, Edwin Lewis, Heidi Goodrich-Blair, Patricia Stock, Byron Adams, Paul Sternberg.

1038B. MAPPS: A high-throughput approach to identify gene function in C. elegans. Calvin Mok, M. Edgley, L. Gevirtzman, DG. Moerman, RH. Waterston.

1039C. Genetic mapping of hybrid developmental delay with novel near-isogenic lines of Caenorhabditis briggsae. Jordan Montgomery, Joseph Ross.

1040A. Comprehensive identification of worm and fly transcription factor binding sites. modERN consortium, V. Reinke, M. Gerstein, S. Celnicker, KP White, RH Waterston.

1041B. Improved C. briggsae genome assembly. Philipp Kaempfer, Mathew Tinney, Stephanie Merret, Sylke Winkler, Andreas Dahl, Siegfried Schloissnig, Mihail Sarov.

1042C. Genomic determinants of the entomopathogenic lifestyle from independently arising nematodes. Hillel Schwartz, Adler Dillman, Paul Sternberg.

1043A. Using C. elegans to discover functions of conserved unknown human genes. Erich M. Schwarz, Shawn J. Kim, Xiawei Huang, Ravi D. Nath, Srimoyee Ghosh, Paul W. Sternberg.

1044B. Comparing software for mutation identification from whole-genome sequence data. Sijung Yun, Michael Krause, Harold Smith.

1045C. Risk of gene deletion in worms with impaired DNA repair machinery. Yuji Suehiro, Sawako Yoshina, Tomoko Motohashi, Satoru Iwata, Katsufumi Dejima, Shohei Mitani.

1046A. Genomic approaches to study the roles of various splicing factors in regulating alternative splicing events in C. elegans. June Tan, Arun K. Ramani, Hong Na, Debashish Ray, Quaid Morris, Timothy R. Hughes, Andrew G. Fraser.

1047B. Accelerating gene discovery by phenotyping the deep-sequenced Million Mutation Project strains and using genome-wide statistical analysis approaches. Tiffany Timbers, Stephanie Garland, Katherine Lee, Stephane Flibotte, Swetha Mohan, Mark Edgley, Donald Moerman, Michel Leroux.

1048C. Systematic phenotyping in C. elegans to reveal the effects of natural variation on RNAi perturbations. Victoria Vu, Adrian J. Verster, Michael Schertzberg, Tungalag Chuluunbaatar, Mark Spensley, Djina Pajkic, G. Traver Hart, Jason Moffat, Andrew G. Fraser.

1049A. Investigating multigenarationaleffects of silver nanoparticles on reproduction and genomic instability in C. elegans. A. Wamucho, J. Unrine, O. Tsyusko.

1050B. Illumina Synthetic Long Read Sequencing Allows Recovery of Missing Sequences even in the “Finished” C. elegans Genome. Runsheng Li, Chia-Ling Hsieh, Amanda Young, Zhihong Zhang, Xiaoliang Ren, Zhongying Zhao.

Gene Regulation and Genomics - Novel Genetic Technologies

1051C. Quantification of in vivo stem cell mutation rate. Pete Taylor, Amanda Cinquin, Olivier Cinquin.

1052A. Revisiting the C. elegans maintenance media (CeMM) for automated, multi-generational cultivation, genome-wide analyses and pharmaceutical studies. J. Doh, A. Moore, I. Çelen, M. Moore, C. Sabanayagam.

1053B. Genome-wide analyses of actively translating mRNAs across tissues and specific neuronal cell-types. Xicotencatl Gracida, Mike Dion, John A. Calarco.

1054C. Worm farming: growing and harvesting large quantities of C. elegans. Michael J. Hoy, Emma Watson, Albertha J. M. Walhout.

1055A. Analysis of Eukaryotic Gene Expression Noise in A Negative-Feedback Loop. J. Huang, L. Liu, Y. Zhao.

1056B. Genetic engineering of new balancers using by CRISPR/Cas9 genome-editing system in Caenorhabditis elegans. S. Iwata, S. Yoshina, S. Mitani.

1057C. MegaTIC: a dual selection-based strategy for genome engineering in C.elegans. T. JI, P. Ibáńez Cruceyra, M. D'alessandro, J. Bessereau.

1058A. Efficient genome editing catalyzed by Mos transposase expressed from single copy integrated transgenes. Swetha Ramani Joswala, Aaron Severson.

1059B. The accessible chromatin of the C. elegans genome. Jürgen Jänes, Yan Dong, Carolina Gemma, Djem Kissiov, Daniel Gaffney, Julie Ahringer.

1060C. Using hlh-8 to model craniofacial diseases in C. elegans. Sharon Kim, Andy Golden, Ann Corsi.

1061A. Tissue-specific gene expression profiling by direct RNA tagging identified novel long-noncoding RNAs . Xiaopeng Ma, Ge Zhan, Enchao Yu, Michael Zhang, Xiao Liu.

1062B. MIP-MAP: A high-throughput method for mapping C. elegans mutant alleles. Calvin Mok, OA. Thompson, V. Au, M. Edgley, L. Gervirtzman, DG. Moerman, RH. Waterston.

1063C. Optogenetic mutagenesis using a reactive-oxygen-species generator, miniSOG. Kentaro Noma, Yishi Jin.

1064A. Rapid and efficient generation of targeted knock-ins and knock-outs using dual selectable/screenable cassettes for template-guided repair of CRISPR/Cas9-mediated breaks. Adam Norris, Hyun-Min Kim, Monica Colaiacovo, John Calarco.

1065B. Low-cost LED-based Fluorescence Dissecting Stereomicroscope for multiple Fluorophores. Andy Papp, John Biondo.

1066C. Simplified efficient C. elegans Microinjection. Andy Papp.

1067A. Global measurement of protein localization in C. elegans with tissue and subcellular specificity. Aaron Reinke, Eric Bennett, Emily Troemel.

1068B. Genome engineering based protein tagging. Dana Suchold, Susanne Ernst, Elisabeth Loester, Mihail Sarov.

1069C. A Golden-Gate plasmid toolkit for high-efficiency combined sgRNA/repair template plasmid generation and CRISPR line isolation. Matthew Schwartz, Erik Jorgensen.

1070A. Rapid discovery of novel mutations using saturation mutagenesis in vivo. T. Shapira, P. Ebert.

Gene Regulation and Genomics - RNA Interference and noncoding RNAs

1071B. An Environmentally Responsive 22G RNA Sensor. Adriel Ablaza, Fernando Munoz-Lobato, Katie Mellman, Sanjeev Balakrishnan, Chantal Brueggemann, Bi-Tzen Juang, Maria Gallegos, Noelle L'Etoile.

1072C. Proteomic analysis of the nuclear RNAi pathway identifies EMB-4/AQR in transposable element regulation. Alper Akay, Mark Larance, Tomas Di Domenico, Ragini Medhi, George Allen, Charles Bradshaw, Angus I. Lamond, Eric A. Miska.

1073A. Olfactory Sensory Neuron Regulation of the Germline in Response to Environment. Aarati Asundi, Atsushi Suzuki, Andrei Goga, Noelle L'Etoile.

1074B. RNA Helicase A May Function to Upregulate Genes in the ALG-3/ALG-4 26G RNA Interference Pathway. Grace P. Bacon, Katherine M. Walstrom.

1075C. Sex- and tissue-specific regulation of RNA interference. Alexandra Bezler, Laurent Keller.

1076A. Abundant small RNAs in C. elegans have predictable features and include a class of 1-nt-staggered clusters of RNAs. Andrew Blumenfeld, Antony Jose.

1077B. Extracellular vesicle (ecv)RNA in C. elegans. Fabian Braukmann, Eric Miska.

1078C. Investigating the Functionality of LincRNAs in C. elegans. Gina Caldas, Craig Mello.

1079A. Elimination of length-bias enables northern blotting to complement RNA-Seq analysis of small RNAs. Yun Choi, Lanelle Edwards, DiBello Aubrey, Antony Jose.

1080B. Comparative Functional Characterization of the CSR-1 22G-RNA Pathway in Caenorhabditis. Monica Wu, Shikui Tu, Jie Wang, Asher Cutter, Zhiping Weng, Claycomb Julie.

1081C. NHL-2 is a novel co-factor of the CSR-1 and WAGO 22G RNA pathways to maintain optimal germline function.. Gregory M. Davis, Shikui Tu, Michelle Francisco, Zhiping Weng, Julie M. Claycomb, Peter R. Boag.

1082A. Rational design of protein coding sequences that evade piRNA-mediated germline silencing. Daniel J. Dickinson, Bob Goldstein.

1083B. Investigation of germ line specific argonaute WAGO-4 and its role in exogenous RNAi pathway and programmed cell death. Luca Ducoli, Martin Keller, Michael O. Hengartner.

1084C. Implication of a new post-translational modifier in microRNA-mediated gene regulation. Lucile Fressigné, Gabriel D. Bossé, Sandra Piquet, Martin J. Simard.

1085A. VET-2 interacts with CSR-1 in C.elegans early embryos. Krishna Ghanta, Masaki Shirayama, Craig Mello.

1086B. Developmentally regulated rapid degradation of specific miRNAs. Rajani Gudipati, Gert-Jan Hendriks, Dimos Gaidatzis, Stephane Thiry, Helge Grosshans.

1087C. Defects in miRNA biosynthesis leads to decline in proteostasis. Nihal Gulseren-Cakmakci, Isa Ozdemir, Funda Sar.

1088A. Environmentally induced small-RNAs inheritance. Leah Houri-Ze'evi, Sarit Anava, Oded Rechavi.

1089B. Autoactivation of lin-4 miRNA Expression in C. elegans Development. A. Jiao, D. Foster, J. Dixon, A. Bauer, F. J. Slack.

1090C. 21U RNAs are required for a proper 22G RNA reset. Rene Ketting, Bruno de Albuquerque, Maria Placentino.

1091A. Mechanism and regulation of piRNA biogenesis in the C. elegans germline. J. Kosalka, EM. Weick, E. Miska.

1092B. RNA editing is important for regulation of RNAi mechanism. Boaz Goldstein, Lily Agranat-Tamir, Ayelet Lamm.

1093C. Regulation of DCR-1-dependent RNAi pathways through DCR-1 phosphorylation. Ahilya Sawh, Alexandra Lewis, James Wohlschlegel, Thomas Duchaine.

1094A. Screen for Micro-RNA Activation of the Dietary Restriction Pathway and for Effect of Micro-RNA Deletions on Fitness in Caenorhabditis elegans. Andrew Liebau, Monica Driscoll, Mehul Vora.

1095B. A worm lincRNA plays a role in dauer constitutive control. Yongjun Li, Pengpeng Liu, Lijiang Long, Zuoyan Zhu, Dong Liu.

1096C. Using C. elegans as a Tool to Decipher the Mechanisms of Extracellular Small RNA Pathways in the Parasitic Nematode, H. polygyrus. Amy Buck, Tuhin Maity, Franklin Chow, Georgios Koutsovoulos, Cesare Ovando-Vázquez, Mark Blaxter, Cei Abreu-Goodger, Julie Claycomb.

1097A. A novel genetic approach to identify new factors implicated in Argonaute-dependent repression of mRNA. Pascale Michaud, Guillaume Jannot, Martin J. Simard.

1098B. Exploring roles for C. elegans Argonaute/small RNA pathways in splicing. Amena Nabih, Shikui Tu, Christopher J. Wedeles, Zhiping Weng, Julie M. Claycomb.

1099C. Modified OP50 E. coli expressing dsRNA elicite a robust RNA interference response in C. elegans. Isaiah Neve, Jessica Sowa, Meng Wang.

1100A. Biochemical and computational characterization of miRNA biosynthesis protein PASH-1 and its mutant PASH-1 C515Y. Isa Ozdemir, Nihal Gulseren-Cakmakci, Funda Sar.

1101B. piRNAs and transgenerational RNA interference protect essential genes from RNA silencing in C. elegans. Carolyn Phillips, Gary Ruvkun, Taiowa Montgomery.

1102C. Systematic analysis of the role of ALG-1 phosphorylation in the miRNA pathway. Miguel Quevillon Huberdeau, Judith Hauptmann, Sandra Piquet, Gunter Meister, Martin J. Simard.

1103A. Ingested RNA engages multiple gene silencing mechanisms that can be inhibited within tissues that express repetitive DNA in C. elegans. Pravrutha Raman, Soriayah Zaghab, Edward Traver, Antony Jose.

1104B. Mobile RNA and intracellularly transcribed RNA silence genes using distinct mechanisms in C.elegans. S. Ravikumar, S. Devanapally, A. M. Jose.

1105C. Expression pattern of C. elegans Y RNA homologs. Manami Sato, Shinya Kihara, Chisato Ushida.

1106A. An investigation on the role of miRNAs as vectors of nicotine-induced imprinting in C. elegans. F. Taki, X. Pan, MH. Lee, B. Zhang.

1107B. Characterization of microRNA associated complexes by MUDPIT proteomics. I. Veksler-Lublinsky, A. Y. Zinovyeva, A. A. Vashisht, J. A. Wohlschlegel, V. Ambros.

1108C. TEG-1 CD2BP2 regulates miRNA levels via maintaining miRISC stability in C. elegans and human cells. Chris Wang, Pratyush Gupta, Gabriel Bossé, Xin Wang, Martin Simard, Dave Hansen.

1109A. Exploring the Roles of the Argonaute CSR-1 in Modulating Chromatin and Protecting Germline Gene Expression. Christopher J. Wedeles, Shikui Tu, Michelle A. Francisco, Zhiping Weng, Julie M. Claycomb.

1110B. Microevolution of microRNAs: developmental profiles and target recognition within C.remanei and C.latens. John Willis, Janna Fierst, Patrick Phillips.

1111C. ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Anna Zinovyeva, Isana Veksler-Lublinsky, Ajay Vashisht, James Wohlschlegel, Victor Ambros.

Cell Biology - Cell Cycle, Cell Division, Meiosis and Chromosome Dynamics

1112A. Motion-based visualization for cytoplasmic streaming. C. Atupelage, K. Kyoda, S. Onami, H. Nagahashi.

1113B. The Protease Activity of Separase Is Required for Both of Chromosome Segregation and Regulation of Membrane Trafficking During Cytokinesis. Xiaofei Bai, Diana Mitchell, Lindsey Klebanow, Joshua Bembenek.

1114C. A novel pathway for the degradation of cyclin B. Riju S. Balachandran, Cassandra S. Heighington, Natalia G. Starostina, Edward T. Kipreos.

1115A. Fine-scale recombination rate variation on the C. elegans X chromosome. Max Bernstein, Matthew Rockman.

1116B. Characterization of a novel role for ETR-1 in reproduction. Ruby Boateng, Andy Golden, Anna Allen.

1117C. Zygotic genome activation triggers chromosome damage and checkpoint signaling in C.elegans primordial germ cells. Melina Butuci, Ashley Williams, Matthew Wong, Brendan Kramer, Matthew Michael.

1118A. Control of C. elegans germline stem cell cycling speed meets requirements of design to minimize mutation accumulation. Michael Chiang, Amanda Cinquin, Adrian Paz, Ted Meeds, Christopher Price, Max Welling, Olivier Cinquin.

1119B. The C. elegans kinesin-13/MCAK family member KLP-7 acts through kinetochores to limit spindle pole number during oocyte meiotic spindle assembly. Amy Connolly, Kenji Sugioka, Chien-Hui Chuang, Joshua Lowry, Bruce Bowerman.

1120C. Polarity proteins regulate the localization of the spindle-positioning mediator, LET-99 . Eugenel Espiritu, Jui-Ching Wu, Ella Richarson, Lesilee Rose.

1121A. Chromosome segregation during male meiosis in C. elegans. Gunar Fabig, Jan Brugués, Thomas Müller-Reichert.

1122B. The kinetochore to cytoplasm ratio determines the strength of the spindle assembly checkpoint during early embryonic divisions. Matilde Galli, David Morgan.

1123C. Mitosis without cytokinesis: mechanism of the endomitotic divisions of the C. elegans intestine. Matilde Galli, David Morgan.

1124A. Investigating the impact of organismal physiology and tissue architecture on mitosis by in situ live imaging of adult germline stem and progenitor cells. Abigail Gerhold, Myreille Larouche, Paul Maddox, Jean-Claude Labbé.

1125B. Putative Protamines, SPCH-1/2/3 highlight distinct features of C. elegans male fertility. Jennifer Gilbert, Jordan Berry, Dana Byrd, Diana Chu.

1126C. Nuclear pore complex protein MEL-28 associates with active chromatin and regulates chromosome segregation and nuclear envelope assembly. Georgina Gómez-Saldivar, Anita G. Fernandez, Allison Lai, Michael Mauro, Cristina González-Aguilera, Fabio Piano, Peter Meister, Peter Askjaer.

1127A. Approaches aimed at identifying the C. elegans homolog of NBS1. Rachel Harney, Sarit Smolikove.

1128B. The Role of ZTF-15 in the meiotic synapsis checkpoint. Tom Hwang, Alice Ye, Pin-Hsi Chen, Needhi Bhalla.

1129C. top-2 is required for proper chromosome segregation during male meiosis in C. elegans. Aimee Jaramillo-Lambert, Harold Smith, Andy Golden.

1130A. Determining the Role of Histone Variants During Spermatogenesis in C.elegans. Monet Jimenez, Rodrigo Estrada, Margaret Jow, PhD, Diana Chu, PhD.

1131B. The meiotic chromosome axis mediates feedback control of CHK-2 activity during meiosis. Yumi Kim, Nora Kostow, Abby F. Dernburg.

1132C. Correlation of centrosome size and spindle architecture in early C. elegans embryos. Marcel Kirchner, Anthony Hyman, Thomas Müller-Reichert.

1133A. A critical role of C. elegans nuclear envelope protein SAMP-1 in spermatogenesis. Aleksandra Kuzmanov, Alison Deshong, Matyas Gorjanacz, JoAnne Engebrecht.

1134B. SUN protein UNC-84 functions in DNA repair choice in the C. elegans germ line. Katherine Lawrence, Erin Tapley, Kayla Aung, Kevin Hart, JoAnne Engebrecht, Dan Starr.

1135C. Double strand break formation and repair pathway choice during meiosis are mediated by him-5. Nicolas Macaisne, Zebulin Kessler.

1136A. CEP-1 is pro-choice for reproductive health in C. elegans. Abigail Rachele Mateo, Zebulin Kessler, Anita Kristine Jolliffe, Olivia McGovern, Bin Yu, Alissa Nicolucci, Judith Yanowitz, W. Brent Derry.

1137B. The C. elegans Casein Kinase 2α homolog, KIN-3, negatively regulates centrosome assembly. Jeff Medley, Megan Kabara, Mi Hye Song.

1138C. A new model for cell cycle asynchrony during early embryogenesis in C. elegans. Matthew Michael.

1139A. Role of PIG-1/MELK kinase in cytokinesis revealed by a suppressor screen for spd-1(oj5ts) spindle defects. Behrooz Esmaeili, Antonia Sagona, Eva Pablo-Hernando, Liam John Messin, Masanori Mishima.

1140B. PAR-4/LKB1 and anillin prevent myosin from uncoupling cytokinetic furrow and mitotic spindle positions during asymmetric division. A. Pacquelet, P. Uhart, G. Michaux.

1141C. Meiotic Progression and Recombination Modulate the Dynamic State of the Synaptonemal Complex. Divya Pattabiraman, Baptiste Roelens, Marc Presler, Grace Chen, Anne Villeneuve.

1142A. Analysis of foci created by the telomere binding protein POT-1 in C. elegans. Felix Peng, Ludmila Shtessel, Paul Maddox, Shawn Ahmed.

1143B. Regulation of spindle positioning through phosphorylation of LIN-5 in asymmetric cell division. Vincent Portegijs, Lars-Eric Fielmich, Matilde Galli, Sander van den Heuvel.

1144C. Phosphoregulation balance allows successful segregation of chromosomes during male meiosis. Luis Quintanilla, Vanessa Cota, Thais Cintra, Diana Chu.

1145A. Analyzing DNA organization during meiotic chromosome pairing. Sreejith Ramakrishnan*, Idan Gabdank*, Andrew Fire, Anne Villeneuve.

1146B. LIN-39 HOX coordinates cell cycle progression during vulval development. Daniel Roiz, Juan Miguel Escobar Restrepo, Alex Hajnal.

1147C. Germ cell proliferation and quality control in the C.elegans germline. Simona Rosu, Orna Cohen-Fix.

1148A. Characterizing the biophysical properties imparted by H2A variants on the compaction of nucleosomal arrays. I. Saucedo Gonzalez, A. Nabhan, F. Guerrero, G. Narlikar, D. Chu.

1149B. Investigating the role of higher-order chromatin structure during gamete formation. Alyssa Scott, Julia Rigothi, Emily Leonard, Carolyn Turcotte, Megan Romer, Paula Checchi.

1150C. Condensin I Promotes Cohesin Linkages during Early C. elegans Meiosis. M. Sifuentes, S. Wignall, G. Csankovszki.

1151A. Polar body extrusion in the early C. elegans embryo. Erik Szentgyörgyi, Julia König, Thomas Müller-Reichert.

1152B. Resource for computational phenotype screening on nuclear division dynamics in C. elegans RNAi embryos, extracted from Phenobank. Yukako Tohsato, Hatsumi Okada, Koji Kyoda, Shuichi Onami.

1153C. Role of the DNA Damage Sensor, ATR in Meiotic Double Strand Break Repair in C. elegans. Lisa Truong, JoAnne Engebrecht.

1154A. The Molecular Mechanism of Cell Cycle Exit of Primordial Germ Cells in Caenorhabditis elegans. Matthew Wong, Matthew Michael.

1155B. GSP-2 PP1 phosphatase regulates chromosome segregation events during sperm meiotic divisions. Yi-hsiu Lin, Jui-ching Wu.

1156C. The role of CHD-1 in the synapsis checkpoint. Payam Yousefi, Antonia Darragh, Needhi Bhalla.

1157A. Imaging the dynamic chromatin status at specific loci in C. elegans. Bo Zhang, Baohui Chen, Jordan Ward, Bo Huang, Noelle L’Etoile.

Cell Biology - Cell Polarity and Cell Death

1158B. The role of PAR proteins in vesicle recruitment to the apical membrane during lumen expansion in the C. elegans excretory canal. Joshua Abrams, Jeremy Nance.

1159C. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Thijs Koorman, Monique van der Voet, Diana Klompstra, Joăo Ramalho, Susan Nieuwenhuize, Sander van den Heuvel, Jeremy Nance, Mike Boxem.

1160A. ced-9/Bcl-2 gene regulation during starvation-induced apoptosis in the germline. Diego Cevallos Porta, Félix Recillas-Targa, Rosa Navarro.

1161B. Defining the kri-1/ccm1 radiation-induced apoptosis pathway in C. elegans. Eric Chapman, W. Brent Derry.

1162C. BRAP-2 (BRca1 Associated binding Protein 2) promotes germline apoptosis. Dayana R. D'Amora, Queenie Hu, Terrance J. Kubiseski.

1163A. Single molecule analysis of PAR protein complexes during cell polarization. Daniel J. Dickinson, Bob Goldstein.

1164B. Regulation of cell extrusion by miRNA complexes in Caenorhabditis elegans. Vivek Dwivedi, Daniel Denning, Bob Horvitz.

1165C. C. elegans screens on polarized organ morphogenesis identify genes that regulate both polarity and growth . Yong Eun, Hongjie Zhang, Liakot A. Khan, Nan Zhang, Verena Gobel.

1166A. The Putative Neutral Amino Acid Transporter SLC-36.1 is Essential for Phagocytic Lysosome Reformation in C. elegans. Qiwen Gan, Nan Xuan, Kai Liu, Qian Zhang, Junxiang Zhou, Chonglin Yang.

1167B. The aspartyl protease ASP-3 mediates apoptotic cell death in C. elegans. Tsung-Yuan Hsu, Victoria J. Bulter, Aimee W. Kao.

1168C. Determination of functional specificity of autophagic proteins during phagocytosis of apoptotic cells in embryo. Celine Jenzer, Xianghua Liu, Elena Simionato, Tianyou Yao, Celine Largeau, Zheng Zhou, Renaud Legouis.

1169A. Degradation and clearance of the linker cell is coordinated by a novel caspase function and the GTPases rab-35 and arf-6. Lena Kutscher, Ryan Haley, Ying Wang, Zheng Zhou, Shai Shaham.

1170B. Suppressors of pam-1 rescue anterior-posterior axis establishment. Timothy Litz, Arielle Kilner, Ashley Kimble, Kate Power, Eva Jaeger, Rebecca Lyczak.

1171C. qx222 affects apoptotic cell clearance and endocytic trafficking. Jinchao Liu, Junbing Zhang, Bin Liu, Yang Dong, Xiaochen Wang.

1172A. The role of centrosome-cortical contact in one-cell anterior-posterior polarity. Dominique Saturno, Devayu Parikh, Dominic Castanzo, Margaret Williams, Rebecca Lyczak.

1173B. Disruption of Cytoplasmic Asymmetry in One-Cell Embryos Due to Nuclear Pore Disruption in the Germline. Michael J. W. VanGompel, Kathryn Plance, Lesilee S. Rose.

1174C. The MEX-5/6 gradient controls PIE-1 segregation in the cytoplasm of the C. elegans zygote. Youjun Wu, Erik Griffin.

1175A. Identification and Characterization of a C. elegans Rab GTPase 2 Regulator in Phagosome and Endosome Maturation. Jianhua Yin, Yaling Huang, Pengfei Guo, Meiyang Li, Xiaochen Wang.

Cell Biology - Cytoskeleton and Migration

1176B. mRNA decapping enzyme DCAP-2 is involved in morphological diversification of cilia. Takeshi Adachi, Keigo Nagahama, Syunsuke Iwasaki, Syoichi Tanabe, Susumu Izumi.

1177C. Biogenesis in the C. elegans germline syncytium: from nucleation to maturation . Rana Amini, Alexandre St-Pierre-See, Jean-Claude Labbé.

1178A. Microtubule and actin networks function together to move larval P-cell nuclei through constricted spaces. Courtney Bone, Yu-Tai Chang, Natalie Cain, Shaun Murphy, Daniel Starr.

1179B. Building and switching LINC complexes in vivo. Natalie Cain, Daniel Starr.

1180C. Death Associated Protein Kinase (DAPK-1) interacts with microtubule dynamics regulators in epidermal development and wound repair. Marian Chuang, Tiffany Hsiao, Amy Tong, Andrew Chisholm.

1181A. The actin-bundling protein plastin/fimbrin regulates cortical contractility in early C. elegans embryogenesis. Wei Yung Ding, Ronen Zaidel-Bar.

1182B. Directional persistence of initial Q neuroblast migration in Caenorhabditis elegans requires both Fat-like cadherins CDH-3 and CDH-4. Annabel L. P. Ebbing, Teije C. Middelkoop, Marco C. Betist, Ni Ji, Euclides F. Povoa, Lorenzo Rella, Hendrik C. Korswagen.

1183C. Worms and Cancer: Using the C. elegans utse as an in vivo model for studying meprin metalloproteases. Srimoyee Ghosh, Sang Nguyen, Paul Sternberg.

1184A. Dissection of the C. elegans lumenal membrane cytoskeleton with super-resolution imaging techniques and adaptive optics. Boran Han, Shu Jia, Graham Dempsey, Edward Membreno, Xiaowei Zhuang, Verena Gobel.

1185B. The formin EXC-6/INFT-1 is required for normal ovulation. Anna Hegsted, Forrest Wright, David Pruyne.

1186C. Peri-lumenal intermediate filaments and microtubules maintain a single lumen in extending C. elegans excretory canals. Liakot Khan, Hongjie Zhang, Edward Membreno, Verena Gobel.

1187A. Metastasis Upregulated Genes Have Distinct Function in C. elegans Cell Migrations. Sylvia Lopez-Vetrone, Mihoko Kato, Jonathan Liu, Olivia Box Power, Anaud Upadhyaya, John Yim, Paul Sternberg.

1188B. Non-muscle myosin contractility in the neuroblasts influences epidermal morphogenesis. Karina Mastronardi, Denise Wernike, Yun Chen, Alisa Piekny.

1189C. The divergent filamin protein FLN-2 functions parallel to SUN/KASH proteins to move larval P-cell nuclei . Robert E. Monroy, Paul Kuehnert, Yu-Tai Chang, Jonathan Kuhn, Shaun Murphy, Daniel A. Starr.

1190A. Using C. elegans as a model to study Laminopathies. Lira Palmer, Courtney R. Bone, Daniel Starr.

1191B. Roles for formins in the development and function of muscle and myoepithelial cell types. David Pruyne, Anna Hegsted, Lei Mi-Mi, SarahBeth Votra, Forrest Wright.

1192C. Role of Canonical and Non-canonical Wnt signaling in Q neuroblasts migration. Lorenzo Rella, Euclides F. Póvoa, Annabel L. P. Ebbing, Marco Betist, Hendrik C. Korswagen.

1193A. AMPK-related kinase UNC-82 is required for myosin filament elongation in C. elegans striated muscle during cell shape changes. NaTasha Schiller, Christopher Duchesneau, Pamela Hoppe.

1194B. ATX-2, the C. elegans homolog of Human Ataxin-2, Negatively Regulates Centrosome Assembly by Controlling Centrosome Size and Microtubule Behavior. Michael Stubenvoll, Jeff Medley, Mi Hye Song.

1195C. Understanding the mechanism of EFF-1-mediated fusion. C. Valansi, K. Fridman, O. Avinoam, M. Oren-Suissa, B. Podbilewicz.

1196A. The ninein-related protein NOCA-1 organizes non-centrosomal microtubule arrays in diverse tissues by acting individually and in parallel to Patronin. Shaohe Wang, Sophie Quintin, Rebecca A. Green, Dhanya K. Cheerambathur, Stacy D. Ochoa, Arshad Desai, Karen Oegema.

1197B. Spermathecal cell stretch during ovulation correlates with development of the mature actin cytoskeleton. Alison Wirshing, Erin Cram.

1198C. A C. elegans model for Human Antigen R (HuR). Zhe Yang, Matthew Buechner.

Cell Biology - Imaging Methods

1199A. Highly sensitive mass spectrometry approaches (LC-MS/MS, LA-ICP-MS) to study drug-mediated modulations in C. elegans. Julia Bornhorst, Fabian Schumacher, Sudipta Chakraborty, Barbara Crone, Burkhard Kleuser, Erich Gulbins, Uwe Karst, Tanja Schwerdtle, Michael Aschner.

1200B. In vivo monitoring of calcium signaling at the single-cell and tissue levels in the spermatheca of C. elegans. Jeff Bouffard, Anand Asthagiri, Erin Cram.

1201C. Three-dimensional super-CLEM. Edward J. Hujber, Robert J. Hobson, Sean A. Merrill, Erik M. Jorgensen.

1202A. Label-free imaging of C. elegans muscle structure using sum-frequency generation microcopy. Do-Young Kim, Hyunmin Kim, Kyung-Il Joo, Jeong-Hoon Hahm, Kyuhyung Kim, Daewon Moon.

1203B. Fluorescent CRISPR/Cas system to specifically label DNA sequences of the egl-1 locus. Sebastian Luehr, Barbara Conradt.

1204C. Development of a Bessel Beam Sheet Illumination Microscope for Large-Scale 3-D Neural Dynamics in C. elegans. Blake Madruga, William Chen, Edward Polanco, Christopher Carmona, Steve Mendoza, Paul Chin, Tim Sherry, Katsushi Arisaka.

1205A. Reproducible quantification of gene expression in single cells of live adult animals. Alexander Mendenhall, Bryan Sands, Patricia Tedesco, Thomas Johnson, Roger Brent.

1206B. The conformation of specific chromosomal loci and transcribing genes in the C. elegans endoderm. Y. Tyulenev, P. Detampel, B. Lancaster, J. D. McGhee.

Cell Biology - Intracellular Trafficking and Organelles

1207C. C.elegans as a model to study extracellular vesicle biology, dynamics, and function. Jyothi Akella, Juan Wang, Julie Maguire, Malan Silva, David Hall, Maureen Barr.

1208A. The functional characterization of C.elegans F-BAR protein SDPN-1 in endocytic recycling. Adenrele Gleason, Barth Grant.

1209B. CAB-1 has dual functions in dense core vesicle trafficking. Patrick Allaire, Matt Schwartz, Erik Jorgensen.

1210C. PAD-1 prevents extracellular vesicle budding in C. elegans embryos. Katharina Beer, Ann Wehman.

1211A. Extracellular matrix proteins are required for ciliogenesis, polycystin ciliary localization, and male mating behaviors. D. De Vore, R. O'Hagan, M. Barr.

1212B. Fatty acid two-hydroxylase (FATH-1) selectively regulates apical membrane trafficking in the C. elegans intestinal cells. Yuanbao Li, Rong Fu, Hanxi Zheng, Xiong Su, Huimin Zhang.

1213C. Mechanisms of mtDNA copy number control. Bryan Gitschlag, Maulik Patel.

1214A. The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex. Gunther Hollopeter, Jeffrey Lange, Ying Zhang, Thien Vu, Mingyu Gu, Michael Ailion, Eric Lambie, Brian Slaughter, Jay Unruh, Laurence Florens, Erik Jorgensen.

1215B. UNC-16 regulates early steps of synaptic vesicle protein trafficking via LRK-1 and UNC-101. Bikash Choudhary, Madhushree Kamak, Jitendra Kumar, Anjali Awasthi, Takashi Fukuzono, Li Chun, Ken Nguyen, Kunihiro Matsumoto, Naoki Hisamoto, Sandhya Koushika.

1216C. ORAI-1 and STIM-1 are required for ovulation. Charlotte Kelley, Erin Cram.

1217A. VPS-34/VPS-15/BEC-1 recruits TBC-2 to endosomes to inactivate the RAB-5 GTPase. Fiona Law, Jung Hwa Seo, Yousstina Bolis, Ashley Brown, Christian Rocheleau.

1218B. A conserved kinase network regulates C. elegans molting. Vladimir Lazetic, John Yochem, Evguenia Karina, David Fay.

1219C. qx193 affects lysosome integrity and dynamics in C. elegans. Yuan Li, Wei Zou, Baohui Chen, Yanan Sun, Xiaochen Wang.

1220A. “PKG-1 affects OSM-3 clustering at the distal tip of cilia and negatively affects IFT-A particle transport in the distal segment”. Prerana Bhan, Hsin-Yi Huang, Muniesh. M. Shanmugam, Ron Hsieh, Helly Punjabi, Oliver. I. Wagner.

1221B. Ubiquitin conjugating enzymes required for tagging paternal organelles. Paola Molina, Lynn Boyd.

1222C. Identification and characterization of genes controlling gut granule size. Caitlin Morris, Alec Barrett, Jared Delahaye, Greg Hermann.

1223A. Depletion of intermediate filament IFB-1 negatively affects mitochondrial trafficking, development and functionality of C. elegans amphid sensory neurons. Muniesh Muthaiyan Shanmugam, Yen Chang, Gong-Her Wu, Oliver Wagner.

1224B. Genes involved in proton transport are required for the formation of HEBE granule, which is a novel aging- and fasting-responsive organelle. Kenji Nishikori, Rei Takahashi, Mami Sato, Takahiro Tanji, Hirohisa Shiraishi, Ayako Ohashi-Kobayashi.

1225C. A conserved ser/thr kinase UNC-51 and its binding partners are required for axon-dendrite logistics (selective trafficking) in Caenorhabditis elegans. Ken-ichi Ogura, Yoshio Goshima.

1226A. C. elegans CCM-3: A mother’s gift to her fledgling that keeps the traffic moving. Swati Pal, Brent Derry.

1227B. Regulation of GLO-1 Rab GTPase activity in trafficking to gut granules. Olivia Foster, Kim Peloza, My Van Vo, Greg Hermann.

1228C. Investigation of genetic mechanisms of hybrid dysfunction reveals evidence of male mitochondrial transmission. Hanson Mouanoutoua, Chih-Chiun Chang, Brandon Ortega, Leonardo Velazco-Cruz, Joseph Ross.

1229A. Endocytosis controls EFF-1-mediated cell fusion. Ksenia Smurova, Benjamin Podbilewicz.

1230B. Stationary cargo act as local regulators of transport in neurons. Parul Sood, Kausalya Murthy, Aparna Ashok, T. Vinod Kumar, Gautam Menon, Sandhya P. Koushika.

1231C. Characterization of HEBE granules, novel organelles found in the intestine of well-fed young adult C. elegans. Takahiro Tanji, Kenji Nishikori, Syoko Haga, Yusuke Kobayashi, Yuki Kanno, Hirohisa Shiraishi, Ayako Ohashi-Kobayashi.

1232A. Deuteriated polyunsaturated fatty acids protect C. elegans from oxidative stress induced damage. Alisha Chakrabarti, Mikhail S. Shchepinov, Guillaume Thibault.

1233B. RGG mediated assembly of liquid-phase protein droplets comprised of nucleolar proteins. N. Vaidya, C. Brangwynne.

1234C. LRIGs: Novel Regulators of TGF-β / BMP Signaling. Mehul Vora, Ryan Gleason, Nanci Kane, Richard Padgett.

1235A. Calcineurin homologous proteins (CHPs) are essential for the membrane stability of sodium-proton exchangers (NHXs) in C. elegans. Eric Allman, Qian Wang, Rachel Walker, Molly Austen, Maureen Peters, Keith Nehrke.

1236B. qx427 affects lysosome morphology and function in C. elegans. Yanwei Wu, Leiling Shi, Xiaochen Wang.

1237C. SGK-1 negatively regulate membrane trafficking in the intestine of C. elegans. Yijian Yan, Wenjing Qi, Ralf Baumeister.

1238A. Modifier screens of a C. elegans tubular polarity phenotype identify components of a novel vesicle-based pathway for polarized membrane biogenesis. Nan Zhang, Hongjie Zhang, Liakot A. Khan, Verena Gobel.

1239B. MON-2 is Required for Maintaining Lysosome Homeostasis. Junxiang Zhou, Qian Zhang, Youli Jian, Meng Xu, Chonglin Yang.

1240C. Phase transitions in the C. elegans nucleus: the functional implications of concentration-dependent assembly of the nucleolus. Lian Zhu, Stephanie Weber, Joel Berry, Nilesh Vaidya, Mikko Haataja, Clifford Brangwynne.


1241A. Implementing a discovery-based C. elegans lab module in freshman biology courses. Jason Chan, Trisha Staab, BIO122 Class.

1242B. C. elegans as a tool to study gonad development in a small liberal arts context. Meaghan Clark, Audrey Denman, Soobin Dokko, Mara Heilig, Jessica Palacios, Lindsey Scott, Groover Snell, Arika Wieneke, Brenda Zarazua, Matt Crook.

1243C. WormBase - Challenges in gene curation. Paul Davis, Bruce Bolt, Thomas Down, Jane Lomax, Michael Paulini, Gary Williams, Kevin Howe, The WormBase Consortium.

1244A. Pick-free C. elegans Genetics Lab Module. Janet Duerr.

1245B. A laboratory exercise utilizing C. elegans Notch mutants for an undergraduate cancer biology course. Amy C. Groth.

1246C. The Elegant Mind Club: Undergraduate Research Club to Explore the Minds of C. elegans. Michelle Kao, Shirley Cheng, Karen Jiang, Taejoon Kim, Nathaniel Nowak, Leonard Haller, Steve Mendoza, De'Marcu Woolfork, Brian Lam, Neha Agarwal, Tim Sherry, Peter Pellionisz, Bobby Vanmali, Linsay Ling, Blake Madruga, Guillaume Trusz, Addelyn Sagadevan, Sean Atamdede, Amanda Sunyoto, Katsushi Arisaka.

1247A. A modular framework for teaching sequencing based functional genomics to high school students.. Rabi Murad, Marissa Macchietto, Ali Mortazavi, Debra Mauzy-Melitz.

1248B. Outreach from C. elegans Research to Alzheimer’s Patient Care, using Biotech Summer Internship Program.. Shin Murakami, Alexander “Sandy” Halperin.

1249C. Crowd-sourcing worm genetics to bring novel research to a large undergraduate lab class. Jennifer Powell.

1250A. UC Davis-University of Maryland Eastern Shore Graduate Admissions Pathway: Collaborating to broaden participation in molecular and cellular biology. D. Starr, C. Hom.