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Schedule of Events



Friday, March 28   1:45 PM–3:45 PM

Drosophila Male Fertility as a Cell Biological Model


Room:

Pacific Ballroom Salon 7

Organizers:

Julie Brill, The Hospital for Sick Children, Toronto, Canada, and
Mariana Wolfner, Cornell University, Ithaca, New York

This workshop will showcase the exciting progress in Drosophila male fertility research, and at the same time highlight how the special features of the Drosophila male reproductive system provide a powerful way to dissect cell biological processes of general importance. After a brief historical overview, the workshop will feature talks that focus on novel cellular mechanisms that underlie Drosophila spermatogenesis and male fertility. Topics will include recent advances in understanding the biogenesis and function of sperm and accessory gland organelles, mitochondrial morphogenesis, microtubule organization, individualization, exosome biology, and paternal contributions to embryogenesis.

Julie Brill, Hospital for Sick Children and University of Toronto, and Mariana Wolfner, Cornell University: Overview: Drosophila male fertility as a cell biological model

Karen Hales, Davidson College: Genetic control of mitochondrial morphogenesis during Drosophila spermatogenesis

Jieyen Chen, Florida State University: A splice variant of Centrosomin converts mitochondria to MTOCs to facilitate sperm tail elongation

Eli Arama, Weizmann University: The mitochondria as rate-limiting factors for caspase activation during spermatid individualization

Lacramioara (Lala) Fabian, Hospital for Sick Children: Phosphoinositide levels modulate nuclear and chromatin remodeling events during spermiogenesis

Takuo Yamaki, University of Washington: Paternal effect mutations reveal diverse roles of sperm specific chromosomal proteins

Frank W. Avila, Cornell University: Seminal proteins as a model for the mechanism and control of extracellular proteolysis cascades

Clive Wilson, Oxford University: Probing the regulation and function of exosomes in the male accessory gland

Special talk by Dan Lindsley, University of California at San Diego: Model for chemical mutagenesis